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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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I650962-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $150.90 | |
I650962-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $340.90 | |
I650962-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $510.90 |
Flavonoids Isoflavones Phenols Polyphenols
Synonyms | Irisolidone|2345-17-7|4'-O-Methyltectorigenin|4'-Methoxytectorigenin|5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)chromen-4-one|081ORX70ZR|CHEBI:5972|Isoflavone, 5,7-dihydroxy-4',6-dimethoxy-|5,7-Dihydroxy-6,4'-dimethoxyisoflavone|5,7-dihydroxy-6-methoxy-3- |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC 50 =9.8 μM). |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC 50 =9.8 μM) . In Vitro Irisolidone, an isoflavone metabolite, represses JC virus gene expression via inhibition of Sp1 binding in human glial cells. Irisolidone can inhibit endothelial cell proliferation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)chromen-4-one |
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INCHI | InChI=1S/C17H14O6/c1-21-10-5-3-9(4-6-10)11-8-23-13-7-12(18)17(22-2)16(20)14(13)15(11)19/h3-8,18,20H,1-2H3 |
InChi Key | VOOFPOMXNLNEOF-UHFFFAOYSA-N |
Canonical SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C(=C(C(=C3)O)OC)O |
Isomeric SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C(=C(C(=C3)O)OC)O |
PubChem CID | 5281781 |
Molecular Weight | 314.29 |
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Solubility | DMSO : 100 mg/mL (318.18 mM; Need ultrasonic) |
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