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Islatravir - ≥98%, high purity , Human immunodeficiency virus type 1 reverse transcriptase inhibitor, CAS No.865363-93-5, Human immunodeficiency virus type 1 reverse transcriptase inhibitor

  • ≥98%
Item Number
I651561
Grouped product items
SKUSizeAvailabilityPrice Qty
I651561-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$119.90
I651561-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
I651561-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
I651561-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$789.90
I651561-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

Basic Description

SynonymsIslatravir|865363-93-5|4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine|EFdA|MK-8591|Islatravir [USAN]|2'-deoxy-4'-C-ethynyl-2-fluoroadenosine|(2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol|ISLATRAVIR ANHYDROUS|MK-8591
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeINHIBITOR
Mechanism of actionHuman immunodeficiency virus type 1 reverse transcriptase inhibitor

Product Properties

ALogP-0.6

Names and Identifiers

IUPAC Name (2R,3S,5R)-5-(6-amino-2-fluoropurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol
INCHI InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1,5-7,19-20H,3-4H2,(H2,14,16,17)/t6-,7+,12+/m0/s1
InChi Key IKKXOSBHLYMWAE-QRPMWFLTSA-N
Canonical SMILES C#CC1(C(CC(O1)N2C=NC3=C(N=C(N=C32)F)N)O)CO
Isomeric SMILES C#C[C@]1([C@H](C[C@@H](O1)N2C=NC3=C(N=C(N=C32)F)N)O)CO
Alternate CAS 865363-93-5
PubChem CID 6483431
MeSH Entry Terms 2'-deoxy-4'-ethynyl-2-fluoroadenosine;4'-ethynyl-2-fluoro-2'-deoxyadenosine;islatravir;MK-8591;MK8591
Molecular Weight 293.25

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
G2429291Certificate of AnalysisApr 20, 2024 I651561
G2429292Certificate of AnalysisApr 20, 2024 I651561
G2429293Certificate of AnalysisApr 20, 2024 I651561
G2429294Certificate of AnalysisApr 20, 2024 I651561
G2429295Certificate of AnalysisApr 20, 2024 I651561

Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (341.01 mM; Need ultrasonic) H2O : 3.57 mg/mL (12.17 mM; ultrasonic and warming and heat to 60°C)

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H373:Causes damage to organs through prolonged or repeated exposure

H371:May cause damage to organs

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P308+P316:IF exposed or concerned: Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

Related Documents

Solution Calculators