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Islatravir - ≥98%, high purity , Human immunodeficiency virus type 1 reverse transcriptase inhibitor, CAS No.865363-93-5, Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Basic Description Synonyms Islatravir|865363-93-5|4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine|EFdA|MK-8591|Islatravir [USAN]|2'-deoxy-4'-C-ethynyl-2-fluoroadenosine|(2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol|ISLATRAVIR ANHYDROUS|MK-8591 Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Names and Identifiers IUPAC Name (2R,3S,5R)-5-(6-amino-2-fluoropurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol INCHI InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1,5-7,19-20H,3-4H2,(H2,14,16,17)/t6-,7+,12+/m0/s1 InChi Key IKKXOSBHLYMWAE-QRPMWFLTSA-N Canonical SMILES C#CC1(C(CC(O1)N2C=NC3=C(N=C(N=C32)F)N)O)CO Isomeric SMILES C#C[C@]1([C@H](C[C@@H](O1)N2C=NC3=C(N=C(N=C32)F)N)O)CO Alternate CAS 865363-93-5 PubChem CID 6483431 MeSH Entry Terms 2'-deoxy-4'-ethynyl-2-fluoroadenosine;4'-ethynyl-2-fluoro-2'-deoxyadenosine;islatravir;MK-8591;MK8591 Molecular Weight 293.25
Chemical and Physical Properties Solubility DMSO : 100 mg/mL (341.01 mM; Need ultrasonic) H2O : 3.57 mg/mL (12.17 mM; ultrasonic and warming and heat to 60°C)
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS08 Signal Danger Hazard Statements H301: Toxic if swallowed
H373: Causes damage to organs through prolonged or repeated exposure
H371: May cause damage to organs
Precautionary Statements P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P308+P316: IF exposed or concerned: Get emergency medical help immediately.
P319: Get medical help if you feel unwell.
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