Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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I125844-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $68.90 | |
I125844-20mg | 20mg | In stock | $153.90 | |
I125844-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $236.90 | |
I125844-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $426.90 | |
I125844-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $767.90 |
Akt inhibitor. Natural chalcone.
Synonyms | Isobavachalcone|20784-50-3|Corylifolinin|Isobacachalcone|4-Hydroxyisocordoin|ZWO2SC993A|CHEBI:28106|2',4,4'-Trihydroxy-3'-(3-methyl-2-butenyl)chalcone|UNII-ZWO2SC993A|Corylifolinin;Isobacachalcone|(E)-1-(2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4 |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Isobavachalcone inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Isobavachalcone exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Isobavachalcone(Corylifolinin) is a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. |
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IUPAC Name | (E)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
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INCHI | InChI=1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+ |
InChi Key | DUWPGRAKHMEPCM-IZZDOVSWSA-N |
Canonical SMILES | CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)C |
Isomeric SMILES | CC(=CCC1=C(C=CC(=C1O)C(=O)/C=C/C2=CC=C(C=C2)O)O)C |
PubChem CID | 5281255 |
Molecular Weight | 324.38 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2212069 | Certificate of Analysis | Jun 11, 2024 | I125844 |
C2419296 | Certificate of Analysis | Mar 12, 2024 | I125844 |
C2419297 | Certificate of Analysis | Mar 12, 2024 | I125844 |
C2419298 | Certificate of Analysis | Mar 12, 2024 | I125844 |
A2402120 | Certificate of Analysis | Jan 09, 2024 | I125844 |
J2115036 | Certificate of Analysis | Jul 18, 2023 | I125844 |
E1705072 | Certificate of Analysis | Dec 08, 2022 | I125844 |
G2201001 | Certificate of Analysis | Jul 15, 2022 | I125844 |
E2213156 | Certificate of Analysis | May 18, 2022 | I125844 |
Solubility | DMSO |
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Refractive Index | 1.66 |
Boil Point(°C) | ~549.03° C at 760 mmHg |
Melt Point(°C) | 210.09°C |