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Isosakuranetin - 98%, high purity , CAS No.480-43-3, Channel blocker of TRPM3

Moligand™
≥98%

CAS#: 480-43-3
Formula: C₁₆H₁₄O₅
Molecular Weight: 286.28
EC Number: 207-551-8
PubChem CID: 160481
PubChem SID: 488188316

Item Number

I414404

Grouped product items
SKU	Size	Availability	Price
I414404-5mg	5mg	In stock	$540.90
I414404-10mg	10mg	In stock	$849.90
I414404-25mg	25mg	In stock	$1,484.90
I414404-50mg	50mg	In stock	$2,225.90
I414404-100mg	100mg	In stock	$3,341.90

View related series

TRPM3 Channel blocker

Basic Description

Synonyms	Isosakuranetin\|480-43-3\|4'-Methylnaringenin\|Isosakutanetin\|naringenin 4'-methyl ether\|(2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one\|U02X7TF8UA\|(S)-5,7-dihydroxy-2-(4-methoxyphenyl)chroman-4-one\|CHEMBL470266\|CHEBI:27552\|5,7-Dihydroxy-4'-m
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found in Citrus species.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of TRPM3
Product Description	Information Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found inCitrusspecies.

ALogP

2.599

HBD Count

Rotatable Bond

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1B1 Tchem Cytochrome P450 1B1 0 Activities

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 1 Activities

Discover Target: TRPM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Discover Target: FTL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 0 Activities

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

Discover Target: XDH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Discover Target: ACHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BCHE Tclin Cholinesterase 0 Activities

Discover Target: BCHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488188316
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488188316
IUPAC Name	(2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
INCHI	InChI=1S/C16H14O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m0/s1
InChi Key	HMUJXQRRKBLVOO-AWEZNQCLSA-N
Canonical SMILES	COC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O
Isomeric SMILES	COC1=CC=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O
Alternate CAS	480-43-3
PubChem CID	160481
MeSH Entry Terms	isosakuranetin
Molecular Weight	286.28

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

10 results found

Lot Number	Certificate Type	Date	Item
B2327695	Certificate of Analysis	Aug 08, 2022	I414404
B2327696	Certificate of Analysis	Aug 08, 2022	I414404
B2327698	Certificate of Analysis	Aug 08, 2022	I414404
B2327699	Certificate of Analysis	Aug 08, 2022	I414404
B2327700	Certificate of Analysis	Aug 08, 2022	I414404
B2327701	Certificate of Analysis	Aug 08, 2022	I414404
B2327704	Certificate of Analysis	Aug 08, 2022	I414404
B2327705	Certificate of Analysis	Aug 08, 2022	I414404
B2327708	Certificate of Analysis	Aug 08, 2022	I414404
B2327728	Certificate of Analysis	Aug 08, 2022	I414404

Solubility

Solubility (25°C) In vitro DMSO: 57 mg/mL (199.1 mM);

Sensitivity

light & moisture & heat sensitive

DMSO(mg / mL) Max Solubility

DMSO(mM) Max Solubility

199.106215690855

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