Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Specifications & Purity | ≥90% |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Isovaleryl coenzyme A, an intermediate of the leucine catabolism. It is synthesized from β-methylbutyric acid by the action of enzyme acyl CoA synthetase. The conversion of isovaleryl-CoA to methylcrotonyl-CoA is catalyzed by the enzyme isovaleryl-CoA dehydrogenase in leucine catabolism pathway. The enzyme isovaleryl-CoA oxidase also calalyzes this conversion in fatty acid β-oxidation pathway.Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts fromG. reessiiin high-performance liquid chromatography (HPLC) for the characterization of IV-CoA from lymphocytesas a substrate in isovaleryl-CoA dehydrogenase assay |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Related Documents
References
| 1. Lee,Rosazza. (1998-03-28) Enzyme analyses demonstrate that beta-methylbutyric acid is converted to beta-hydroxy-beta-methylbutyric acid via the leucine catabolic pathway by galactomyces reessii. Archives of microbiology, 169 ((3)): (257-262). [PMID:9477261] |
| 2. K Däschner,I Couée,S Binder. (2001-06-13) The mitochondrial isovaleryl-coenzyme a dehydrogenase of arabidopsis oxidizes intermediates of leucine and valine catabolism.. Plant physiology, 126 ((2)): (601-612). [PMID:11402190] |
| 3. Taifo Mahmud,Silke C Wenzel,Eva Wan,Kwun Wah Wen,Helge B Bode,Nikolaos Gaitatzis,Rolf Müller. (2004-12-28) A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway.. Chembiochem : a European journal of chemical biology, 6 ((2)): (322-330). [PMID:15619721] |
| 4. Helge B Bode,Michael W Ring,Gertrud Schwär,Matthias O Altmeyer,Carsten Kegler,Ivy R Jose,Mitchell Singer,Rolf Müller. (2008-10-11) Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus.. Chembiochem : a European journal of chemical biology, 10 ((1)): (128-140). [PMID:18846531] |
| 5. Yu-Ning Liu,Tze-Tze Liu,Ya-Ling Fan,Dau-Ming Niu,Yin-Hsiu Chien,Yen-Yin Chou,Ni-Chung Lee,Kwang-Jen Hsiao,Yen-Hui Chiu. (2015-12-02) Measuring propionyl-CoA carboxylase activity in phytohemagglutinin stimulated lymphocytes using high performance liquid chromatography.. Clinica chimica acta; international journal of clinical chemistry, 453 (13-20). [PMID:26620954] |
| 6. G Tajima,H Yofune,A D Bahagia Febriani,Y Nishimura,H Ono,N Sakura. (2005-01-27) A simple and rapid enzymatic assay for the branched-chain alpha-ketoacid dehydrogenase complex using high-performance liquid chromatography.. Journal of inherited metabolic disease, 27 ((5)): (633-639). [PMID:15669679] |
| 7. Helge B Bode,Michael W Ring,Gertrud Schwär,Reiner M Kroppenstedt,Dale Kaiser,Rolf Müller. (2006-09-06) 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.. Journal of bacteriology, 188 ((18)): (6524-6528). [PMID:16952943] |
| 8. Wolfram Lorenzen,Michael W Ring,Gertrud Schwär,Helge B Bode. (2009-07-21) Isoprenoids are essential for fruiting body formation in Myxococcus xanthus.. Journal of bacteriology, 191 ((18)): (5849-5853). [PMID:19617362] |
| 9. Tobias Bock,Carsten Volz,Vanessa Hering,Andrea Scrima,Rolf Müller,Wulf Blankenfeldt. (2016-12-13) The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.. Nucleic acids research, 45 ((4)): (2166-2178). [PMID:27940564] |