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IWP-3 - 10mM in DMSO, high purity , CAS No.687561-60-0(DMSO)
Basic Description Specifications & Purity 10mM in DMSO Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description IWP-3 is an potent inhibitor of Wnt production with an IC 50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1γ3 and CK1ε only moderately and does not inhibit CK1α.
Names and Identifiers Canonical SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=C(C=C5)F)SCC4 Molecular Weight 484.59
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