IWP-O1 - 98%, high purity , CAS No.2074607-48-8

Item Number

I414094

Grouped product items
SKU	Size	Availability	Price
I414094-5mg	5mg	In stock	$117.90
I414094-10mg	10mg	In stock	$206.90
I414094-25mg	25mg	In stock	$444.90
I414094-50mg	50mg	In stock	$800.90
I414094-100mg	100mg	In stock	$1,434.90

PORCN Inhibitors

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads

Names and Identifiers

IUPAC Name	N-(5-phenylpyridin-2-yl)-2-(5-phenyl-4-pyridin-4-yltriazol-1-yl)acetamide
INCHI	InChI=1S/C26H20N6O/c33-24(29-23-12-11-22(17-28-23)19-7-3-1-4-8-19)18-32-26(21-9-5-2-6-10-21)25(30-31-32)20-13-15-27-16-14-20/h1-17H,18H2,(H,28,29,33)
InChi Key	GYYDQHBKIHQHEB-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)C2=CN=C(C=C2)NC(=O)CN3C(=C(N=N3)C4=CC=NC=C4)C5=CC=CC=C5
Isomeric SMILES	C1=CC=C(C=C1)C2=CN=C(C=C2)NC(=O)CN3C(=C(N=N3)C4=CC=NC=C4)C5=CC=CC=C5
PubChem CID	134154594
Molecular Weight	432.48

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
K2229407	Certificate of Analysis	Oct 10, 2022	I414094
K2229408	Certificate of Analysis	Oct 10, 2022	I414094
K2229457	Certificate of Analysis	Oct 10, 2022	I414094
K2229458	Certificate of Analysis	Oct 10, 2022	I414094
K2229459	Certificate of Analysis	Oct 10, 2022	I414094

Solubility

Solubility (25°C) In vitro DMSO: 86 mg/mL (198.85 mM); Ethanol: 86 mg/mL (198.85 mM); Water: Insoluble;

Sensitivity

Light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
RIDADR	NONHforallmodesoftransport

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Basic Description