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JAK-IN-5 hydrochloride - 99%, high purity , CAS No.J659444

  • ≥99%
Item Number
J659444
Grouped product items
SKUSizeAvailabilityPrice Qty
J659444-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$450.90
J659444-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$800.90
J659444-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,650.90
J659444-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,550.90

Basic Description

Specifications & Purity99%
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
Product Description

JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.

Appearance:Solid

IC50& Target:JAK .

In Vivo:JAK-IN-5 hydrochloride (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction. JAK-IN-5 hydrochloride (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μ

Biological Activity:JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.

Names and Identifiers

Canonical SMILES CN1CCC(N2CC(N=C(C3=NNC4=C3C=CC(C5=C(CC)C=C(O)C(F)=C5)=C4)N6)=C6CC2)CC1.[H]Cl
Molecular Weight 511.03

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 5 mg/mL (9.78 mM; Need ultrasonic) H2O : 0.5 mg/mL (0.98 mM; ultrasonic and warming and heat to 60°C)

Related Documents

Solution Calculators