JB002 is a myosin II inhibitor, with an IC 50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy
In Vitro
JB002 show promising selectivity between cardiac and skeletal myosin but have no detectible activity toward nonmuscle IIB. MCE has not independently confirmed the accuracy of these methods. They are for reference only.