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Jedi2 - ≥98%(HPLC), high purity , CAS No.651005-90-2, Activator of Piezo1

Item Number

J288068

Grouped product items
SKU	Size	Availability	Price
J288068-10mg	10mg	In stock	$147.90
J288068-50mg	50mg	In stock	$583.90
J288068-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,628.90

Piezo1 channel activator

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Basic Description

Synonyms	Jedi2\|651005-90-2\|2-Methyl-5-(thien-2-yl)-3-furoic acid\|2-methyl-5-(thiophen-2-yl)furan-3-carboxylic acid\|2-Methyl-5-(2-thienyl)-3-furancarboxylic acid\|2-methyl-5-(2-thienyl)-3-furoic acid\|CHEMBL5181053\|2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid\|Mayb
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of Piezo1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid
INCHI	InChI=1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
InChi Key	YXDCRSXNEOKXDE-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
Isomeric SMILES	CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
Alternate CAS	651005-90-2
PubChem CID	2796026
Molecular Weight	208.23

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Solubility	Solvent:DMSO, Max Conc. mg/mL: 20.82, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 20.82, Max Conc. mM: 100

1. Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, Rao Y, Zu L, He W, Xiao B. (2018) A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel.. Nat Commun, 9 (1): (1300). [PMID:29610524]

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