Click Here for 5% Off Your First Aladdin Purchase!

JNJ 16259685 - 96%, high purity , CAS No.409345-29-5, Allosteric modulator of mGlu 1 receptor

  • Moligand™
  • ≥96%
Item Number
J287450
Grouped product items
SKUSizeAvailabilityPrice Qty
J287450-5mg
5mg
In stock
$116.90
J287450-10mg
10mg
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$182.90
J287450-25mg
25mg
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$391.90
J287450-50mg
50mg
In stock
$599.90
J287450-100mg
100mg
In stock
$1,080.90

Highly potent, mGlu1-selective non-competitive antagonist

Basic Description

Synonyms409345-29-5|JNJ 16259685|JNJ16259685|JNJ-16259685|(3,4-dihydro-2h-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone|CHEMBL174588|JNJ16259865|3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone|C20H23NO3|(3,4-dihydro-2H-p
Specifications & Purity96%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of mGlu 1 receptor

Associated Targets

GRM1 Tchem Metabotropic glutamate receptor 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488197391
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488197391
IUPAC Name 3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone
INCHI InChI=1S/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3
InChi Key QOTAQTRFJWLFCR-UHFFFAOYSA-N
Canonical SMILES COC1CCC(CC1)C(=O)C2=CC3=CC4=C(N=C3C=C2)OCCC4
Isomeric SMILES COC1CCC(CC1)C(=O)C2=CC3=CC4=C(N=C3C=C2)OCCC4
PubChem CID 11313361
Molecular Weight 325.41

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

10 results found

Lot NumberCertificate TypeDateItem
D23081216Certificate of AnalysisFeb 24, 2023 J287450
D23081218Certificate of AnalysisFeb 24, 2023 J287450
D23081230Certificate of AnalysisFeb 24, 2023 J287450
D23081231Certificate of AnalysisFeb 24, 2023 J287450
D23081234Certificate of AnalysisFeb 24, 2023 J287450
D23081235Certificate of AnalysisFeb 24, 2023 J287450
D23081236Certificate of AnalysisFeb 24, 2023 J287450
D23081237Certificate of AnalysisFeb 24, 2023 J287450
D23081243Certificate of AnalysisFeb 24, 2023 J287450
D23081244Certificate of AnalysisFeb 24, 2023 J287450

Chemical and Physical Properties

SolubilitySolvent:ethanol, Max Conc. mg/mL: 32.54, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 8.14, Max Conc. mM: 25

Related Documents

Solution Calculators