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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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J287450-5mg | 5mg | In stock | $116.90 | |
J287450-10mg | 10mg | Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks. | $182.90 | |
J287450-25mg | 25mg | Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks. | $391.90 | |
J287450-50mg | 50mg | In stock | $599.90 | |
J287450-100mg | 100mg | In stock | $1,080.90 |
Highly potent, mGlu1-selective non-competitive antagonist
Synonyms | 409345-29-5|JNJ 16259685|JNJ16259685|JNJ-16259685|(3,4-dihydro-2h-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone|CHEMBL174588|JNJ16259865|3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone|C20H23NO3|(3,4-dihydro-2H-p |
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Specifications & Purity | 96% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR |
Mechanism of action | Allosteric modulator of mGlu 1 receptor |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Pubchem Sid | 488197391 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488197391 |
IUPAC Name | 3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone |
INCHI | InChI=1S/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3 |
InChi Key | QOTAQTRFJWLFCR-UHFFFAOYSA-N |
Canonical SMILES | COC1CCC(CC1)C(=O)C2=CC3=CC4=C(N=C3C=C2)OCCC4 |
Isomeric SMILES | COC1CCC(CC1)C(=O)C2=CC3=CC4=C(N=C3C=C2)OCCC4 |
PubChem CID | 11313361 |
Molecular Weight | 325.41 |
PubChem CID | 11313361 |
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ChEMBL Ligand | CHEMBL254574 |
CAS Registry No. | 409345-29-5 |
GPCRdb Ligand | JNJ16259685 |
PubChem SID | 488197391 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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D23081216 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081218 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081230 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081231 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081234 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081235 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081236 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081237 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081243 | Certificate of Analysis | Feb 24, 2023 | J287450 |
D23081244 | Certificate of Analysis | Feb 24, 2023 | J287450 |
Solubility | Solvent:ethanol, Max Conc. mg/mL: 32.54, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 8.14, Max Conc. mM: 25 |
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