JNJ-7777120 - ≥98% (HPLC), high purity , CAS No.459168-41-3, Antagonist of H 4 receptor

Item Number

J129258

• Synonyms: 459168-41-3|JNJ-7777120|JNJ7777120|JNJ 7777120|1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine|(5-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone|(5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone|1-((5-chloro-1H-indol-2-yl)carbonyl
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: JNJ7777120 is a potent, selective non-imidazole H4 histamine receptor antagonist.Potent, highly selective histamine H 4 receptor antagonist (K i = 4.5 nM). Shows anti-inflammatory, antifibrotic and antiallergic effects in vivo.
• Shipped In: Normal
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Antagonist of H 4 receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.
A H4 histamine receptor antagonist.