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Ligand-gated ion channels
JNJ1930942 , CAS No.929562-28-7, Allosteric modulator of nicotinic acetylcholine receptor α7 subunit

JNJ1930942 , CAS No.929562-28-7, Allosteric modulator of nicotinic acetylcholine receptor α7 subunit

Item Number

J611258

Grouped product items
SKU	Size	Availability	Price	Qty
J611258-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$300.90
J611258-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$940.90

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Basic Description

Synonyms	929562-28-7\|(2-((4-Fluoro-3-(trifluoromethyl)phenyl)amino)-4-(pyridin-4-yl)thiazol-5-yl)methanol\|JNJ-1930942\|JNJ1930942\|CHEMBL270479\|5-Thiazolemethanol, 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4-pyridinyl)-\|2-[[4-fluoro-3-(trifluoromethyl)phenyl]
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of nicotinic acetylcholine receptor α7 subunit

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(2-{[4-fluoro-3-(trifluoromethyl)phenyl]amino}-4-(pyridin-4-yl)-1,3-thiazol-5-yl)methanol
INCHI	InChI=1S/C16H11F4N3OS/c17-12-2-1-10(7-11(12)16(18,19)20)22-15-23-14(13(8-24)25-15)9-3-5-21-6-4-9/h1-7,24H,8H2,(H,22,23)
InChi Key	JBSVHWCIKVSTTH-UHFFFAOYSA-N
Canonical SMILES	OCc1sc(nc1c1ccncc1)Nc1ccc(c(c1)C(F)(F)F)F
Isomeric SMILES	C1=CC(=C(C=C1NC2=NC(=C(S2)CO)C3=CC=NC=C3)C(F)(F)F)F
PubChem CID	44240744

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