kb-NB142-70 - 98%, high purity , CAS No.1233533-04-4, Inhibitor of protein kinase D1

Item Number

N275808

• Synonyms: kb NB 142-70|1233533-04-4|3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one|kb-NB142-70|9-hydroxy-3,4-dihydro-2H-[1]benzothiolo[2,3-f][1,4]thiazepin-5-one|3,4-Dihydro-9-hydroxy-[1]benzothieno-[2,3-f]-1,4-thiazepin-5(2H)-one|CHEMBL1672571
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Selective protein kinase D inhibitor (IC 50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). Inhibits prostrate cancer cell migration and invasion and reduces wound healing in vitro. Cytotoxic and anti-proliferative.kb-NB142-70 is a deri
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of protein kinase D1
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at Room Temperature. The product can be stored for up to 12 months.

product description：

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). Kb NB 142-70 inhibits prostate cancer cell migration and invasion and reduces wound healing in vitro. Kb NB 142-70 displays prominent cytotoxic and anti-proliferative effects.