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KH CB19 - >97%, high purity , CAS No.1354037-26-5, Inhibitor of CDC like kinase 1;Inhibitor of CDC like kinase 3;Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A

Moligand™
≥97%

CAS#: 1354037-26-5
Formula: C₁₅H13Cl₂N₃O₂
Molecular Weight: 338.19
PubChem CID: 44237094

Item Number

K335958

Grouped product items
SKU	Size	Availability	Price	Qty
K335958-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$94.90
K335958-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$414.90

a potent and selective inhibitor of CLK1 and CLK4 (CDC2-like kinase 1 and 4)

View related series

CDC like kinase 1 Inhibitor CDC like kinase 3 Inhibitor dual specificity tyrosine phosphorylation regulated kinase 1A Inhibitor

Basic Description

Specifications & Purity	>97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of CDC like kinase 1;Inhibitor of CDC like kinase 3;Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A
Product Description	KH CB19 is a potent and selective inhibitor of CDC2-like kinase (CLK) 1 and 4. KH CB19 suppresses serine/arginine-rich protein phosphorylation by CLKs under proinflammatory conditions.

Associated Targets

DYRK1A Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 Activities

Discover Target: DYRK1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CLK3 Tchem Dual specificity protein kinase CLK3 1 Activities

Discover Target: CLK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CLK1 Tchem Dual specificity protein kinase CLK1 3 Activities

Discover Target: CLK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methylindole-2-carboxylate
INCHI	InChI=1S/C15H13Cl2N3O2/c1-3-22-15(21)14-11(8(6-18)7-19)9-4-5-10(16)12(17)13(9)20(14)2/h4-6H,3,18H2,1-2H3/b8-6-
InChi Key	CXJCGSPAPOTTSF-VURMDHGXSA-N
Canonical SMILES	CCOC(=O)C1=C(C2=C(N1C)C(=C(C=C2)Cl)Cl)C(=CN)C#N
Isomeric SMILES	CCOC(=O)C1=C(C2=C(N1C)C(=C(C=C2)Cl)Cl)/C(=C\N)/C#N
PubChem CID	44237094
Molecular Weight	338.19

ChEMBL Ligand

DrugBank Ligand

PubChem CID

CAS Registry No.

RCSB PDB Ligand

Solubility

Soluble in DMSO (40 mM).

Refractive Index

n20D1.62 (Predicted)

Boil Point(°C)

~604.1° C at 760 mmHg (Predicted)

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KH CB19 - >97%, high purity , CAS No.1354037-26-5, Inhibitor of CDC like kinase 1;Inhibitor of CDC like kinase 3;Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A

Basic Description

Associated Targets

DYRK1A Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 Activities

CLK3 Tchem Dual specificity protein kinase CLK3 1 Activities

CLK1 Tchem Dual specificity protein kinase CLK1 3 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

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