| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| K655569-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $605.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4 , with an IC 50 of 16.5 nM for CLK1 . KH-CB20 can also inhibit DYRK1A ( IC 50 =57.8 nM) and CLK3 ( IC 50 =488 nM) In Vitro KH-CB20 shows selectivity for CLK1 (IC 50 =16.5 nM) over DYRK1A (IC 50 =57.8 nM) and CLK3 (IC 50 =488 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:CLK1 16.5 nM (IC 50 ) DYRK1A 57.8 nM (IC 50 ) CLK3 488 nM (IC 50 ) |
| Canonical SMILES | CCOC(C1=C(C2=C(C(Cl)=C(C=C2)Cl)N1C)/C(C#N)=C\\N)=O |
|---|---|
| Molecular Weight | 338.19 |
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