KKI 5, CAS No.97145-43-2

Features and benefits
    Item Number
    K338116
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    K338116-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $71.90
    K338116-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $285.90

    a Kallikrein Inhibitor

    Basic Description

    Product NameKKI 5, CAS No.97145-43-2
    SynonymsDTXSID90914102 | (S)-2-((3S,6S,9S,12S)-1-((S)-1-acetylpyrrolidin-2-yl)-3-benzyl-6-(3-guanidinopropyl)-9-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecanamido)pentanediamide | 2-{[13-(1-Acetylpyrrolidin-2-yl)-11-benzyl-8-(3-carbamim
    Product Description

    KKI 5 (Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2) is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. In various cancer cell lines, KKI 5 alters membrane potential and increases intracellular Ca|2+|, inhibiting cell proliferation.

    SequenceAc-Pro-Phe-Arg-Ser-Val-Gln-NH2

    Mechanisms of Action

    Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

    Product Specifications

    Storage TempStore at -20°C
    Shipped InIce chest + Ice pads
    CAS97145-43-2

    Certificates

    Certificate of Analysis(COA)

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    Chemical and Physical Properties

    Refractive Indexn20D1.65 (Predicted)
    Melt Point(°C)222° C

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