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Basic Description Product Name KKI 5, CAS No.97145-43-2 Synonyms DTXSID90914102 | (S)-2-((3S,6S,9S,12S)-1-((S)-1-acetylpyrrolidin-2-yl)-3-benzyl-6-(3-guanidinopropyl)-9-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecanamido)pentanediamide | 2-{[13-(1-Acetylpyrrolidin-2-yl)-11-benzyl-8-(3-carbamim Product Description KKI 5 (Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2) is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. In various cancer cell lines, KKI 5 alters membrane potential and increases intracellular Ca|2+|, inhibiting cell proliferation.
Sequence Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Product Specifications Storage Temp Store at -20°C Shipped In Ice chest + Ice pads CAS 97145-43-2
Chemical and Physical Properties Refractive Index n20D1.65 (Predicted) Melt Point(°C) 222° C
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