Kolliphor® EL - pH range: 6.0-8.0, high purity , CAS No.61791-12-6

  • pH range: 6.0-8.0
Item Number
K400327
Grouped product items
SKUSizeAvailabilityPrice Qty
K400327-50g
50g
In stock
$16.90
K400327-250g
250g
In stock
$64.90

Basic Description

Synonyms2-[1,3-bis[2-[(Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [(Z)-11-hydroxyheptadec-8-enyl] carbonate
Specifications & PuritypH range: 6.0-8.0
Legal InformationKolliphor is a registered trademark of BASF
Shipped InNormal
Product Description

A derivative of castor oil and ethylene oxide.
Used to emulsify and solubilize oils and other water-insoluble substances. Cremophor is the brand name for a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only.

Names and Identifiers

IUPAC Name 2-[1,3-bis[2-[(Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [(Z)-11-hydroxyheptadec-8-enyl] carbonate
INCHI InChI=1S/C63H116O15/c1-4-7-10-31-40-57(64)43-34-25-19-13-16-22-28-37-46-73-61(67)76-51-49-70-55-60(72-53-54-78-63(69)75-48-39-30-24-18-15-21-27-36-45-59(66)42-33-12-9-6-3)56-71-50-52-77-62(68)74-47-38-29-23-17-14-20-26-35-44-58(65)41-32-11-8-5-2/h25-27,34-36,57-60,64-66H,4-24,28-33,37-56H2,1-3H3/b34-25-,35-26-,36-27-
InChi Key LXZHFNATOMRESM-AAKVHIHISA-N
Canonical SMILES CCCCCCC(CC=CCCCCCCCOC(=O)OCCOCC(COCCOC(=O)OCCCCCCCC=CCC(CCCCCC)O)OCCOC(=O)OCCCCCCCC=CCC(CCCCCC)O)O
Isomeric SMILES CCCCCCC(O)C/C=C\CCCCCCCOC(=O)OCCOCC(OCCOC(=O)OCCCCCCC/C=C\CC(O)CCCCCC)COCCOC(=O)OCCCCCCC/C=C\CC(O)CCCCCC
WGK Germany 1
RTECS GO5661000
PubChem CID 154733643

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

21 results found

Lot NumberCertificate TypeDateItem
E2428307Certificate of AnalysisMay 20, 2024 K400327
E2428306Certificate of AnalysisMay 20, 2024 K400327
E2428305Certificate of AnalysisMay 20, 2024 K400327
A2404307Certificate of AnalysisDec 23, 2023 K400327
D2417022Certificate of AnalysisDec 23, 2023 K400327
A2404324Certificate of AnalysisDec 23, 2023 K400327
A2404323Certificate of AnalysisDec 23, 2023 K400327
A2404306Certificate of AnalysisDec 23, 2023 K400327
L2125444Certificate of AnalysisSep 22, 2023 K400327
H2301554Certificate of AnalysisJul 05, 2023 K400327
H2301555Certificate of AnalysisJul 05, 2023 K400327
H2301660Certificate of AnalysisJul 05, 2023 K400327
H2301668Certificate of AnalysisJul 05, 2023 K400327
H2301671Certificate of AnalysisJul 05, 2023 K400327
H2301751Certificate of AnalysisJul 05, 2023 K400327
L2307136Certificate of AnalysisJul 05, 2023 K400327
D23141138Certificate of AnalysisDec 14, 2021 K400327
D2327035Certificate of AnalysisDec 14, 2021 K400327
D23141110Certificate of AnalysisDec 14, 2021 K400327
F2327410Certificate of AnalysisDec 14, 2021 K400327
L2214041Certificate of AnalysisDec 14, 2021 K400327

Show more⌵

Chemical and Physical Properties

Flash Point(°C)257°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 1
RTECS GO5661000

Related Documents

Citations of This Product

1. Xiaoqiang Zeng, Hongwu Sun, Yan Ye, Xing Luo, Dingyi Cai, Yun Yang, Ting Chen, Cun Sun, Shaotong Zhang, Hao Zeng.  (2023)  Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus (MRSA) Infection.  Jove-Journal of Visualized Experiments,    (199): (e65152).  [PMID:37677037] [10.3791/65152]
2. Wei Su, Xiantao Jiang, Ying Zhang, Chenxiang Lin, Jun'an Xiao, Peiyuan Li.  (2023)  Photothermal-driven disassembly of naphthalocyanine nano-photosensitizers for photothermal and photodynamic therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  647  (201).  [PMID:37247483] [10.1016/j.jcis.2023.05.113]
3. Yanming Wang, Zhang Chenghao, Zhaoli Wu, Xinran Cui, Jinmei Ren, Jingling Tang.  (2023)  In vivo and in vitro evaluation of pulmonary administration of itraconazole nanostructured lipid carriers for pulmonary aspergillosis.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,      [PMID:37039088] [10.1080/03639045.2023.2200533]
4. Qian-Qian Han, Peng-Fei Wu, Yi-Heng Li, Yu Cao, Jian-Guo Chen, Fang Wang.  (2022)  SVCT2–mediated ascorbic acid uptake buffers stress responses via DNA hydroxymethylation reprogramming of S100 calcium-binding protein A4 gene.  Redox Biology,  58  (102543).  [PMID:36436457] [10.1016/j.redox.2022.102543]
5. Gu Zhengqing, Xue Yuanyuan, Li Shuang, Adu-Frimpong Michael, Xu Ying, Yu Jiangnan, Xu Ximing, Zhu Yuan.  (2022)  Design, Characterization, and Evaluation of Diosmetin-Loaded Solid Self-microemulsifying Drug Delivery System Prepared by Electrospray for Improved Bioavailability.  AAPS PHARMSCITECH,  23  (4): (1-16).  [PMID:35381887] [10.1208/s12249-022-02263-3]
6. Haohui Shi, Na Liang, Jiyang Liu, Siyi Li, Xianfeng Gong, Pengfei Yan, Shaoping Sun.  (2021)  AIE-active polymeric micelles based on modified chitosan for bioimaging-guided targeted delivery and controlled release of paclitaxel.  CARBOHYDRATE POLYMERS,  269  (118327).  [PMID:34294339] [10.1016/j.carbpol.2021.118327]
7. Wenquan Huang, Yuehua Deng, Liping Ye, Qiuling Xie, Yanbin Jiang.  (2021)  Enhancing hemocompatibility and the performance of Au@silica nanoparticles by coating with cRGD functionalized zein.  Materials Science & Engineering C-Materials for Biological Applications,  125  (112064).  [PMID:33965097] [10.1016/j.msec.2021.112064]
8. Kang Sha, Qianfang Ma, Hanitrarimalala Veroniaina, Xiaole Qi, Jiayi Qin, Zhenghong Wu.  (2021)  Formulation optimization of solid self-microemulsifying pellets for enhanced oral bioavailability of curcumin.  PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY,  26  (5): (549-558).  [PMID:33688786] [10.1080/10837450.2021.1899203]
9. Wei Liu, Zehua Li, Kai Yang, Peilong Sun, Ming Cai.  (2021)  Effect of nanoemulsion loading finger citron (Citrus medica L. var. Sarcodactylis) essential oil on human gut microbiota.  Journal of Functional Foods,  77  (104336).  [PMID:] [10.1016/j.jff.2020.104336]
10. Ying Xie, Sen-Ling Feng, Chu-Tian Mai, Yan-Fang Zheng, Hui Wang, Zhong-Qiu Liu, Hua Zhou, Liang Liu.  (2021)  Suppression of up-regulated LXRα by silybin ameliorates experimental rheumatoid arthritis and abnormal lipid metabolism.  PHYTOMEDICINE,  80  (153339).  [PMID:33038868] [10.1016/j.phymed.2020.153339]
11. Ke Zhou, Yixin Zhu, Xuling Chen, Lingbing Li, Wei Xu.  (2020)  Redox- and MMP-2-sensitive drug delivery nanoparticles based on gelatin and albumin for tumor targeted delivery of paclitaxel.  Materials Science & Engineering C-Materials for Biological Applications,  114  (111006).  [PMID:32993973] [10.1016/j.msec.2020.111006]
12. Luyang Lu, Ping Yang, Tian Chen, Yanfu Shen, Qian Yao, Jun Yan.  (2020)  Changes in Biological Activities after Olive Oil, Pomegranate Seed Oil, and Grape Seed Oil were Formulated into Self-Nanoemulsifying Systems.  Journal of Oleo Science,      [PMID:31941867] [10.5650/jos.ess19255]
13. Siyu Guan, Qianqian Zhang, Jianwei Bao, Tijie Duan, Rongfeng Hu, Tori Czech, Jihui Tang.  (2020)  Phosphatidylserine targeting peptide-functionalized pH sensitive mixed micelles for enhanced anti-tumor drug delivery.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,  147  (87).  [PMID:31899369] [10.1016/j.ejpb.2019.12.012]
14. Ze-hua Li, Ming Cai, Kai Yang, Pei-long Sun.  (2019)  Kinetic study of d-limonene release from finger citron essential oil loaded nanoemulsions during simulated digestion in vitro.  Journal of Functional Foods,  58  (67).  [PMID:] [10.1016/j.jff.2019.04.056]
15. Yi Zhang, Haijie Zhao, Xiaozhen Wang, Hehan Xiao, Yanqing Guan.  (2019)  Effects of Cremophor EL/ethanol/oleinic acid/water microemulsion on human blood components and coagulation function.  COLLOIDS AND SURFACES B-BIOINTERFACES,  180  (254).  [PMID:31059983] [10.1016/j.colsurfb.2019.04.058]
16. Xu Peng, Zhou Hua, Li Ya-Zhuo, Yuan Zhong-Wen, Liu Chang-Xiao, Liu Liang, Xie Ying.  (2018)  Baicalein Enhances the Oral Bioavailability and Hepatoprotective Effects of Silybin Through the Inhibition of Efflux Transporters BCRP and MRP2.  Frontiers in Pharmacology,    [PMID:30416442] [10.3389/fphar.2018.01115]
17. Shengcai Yang, Dawei Zhang, Na Shen, Guanyi Wang, Zhaohui Tang, Xuesi Chen.  (2018)  Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species.  JOURNAL OF CELLULAR BIOCHEMISTRY,  120  (1): (634-644).  [PMID:30256439] [10.1002/jcb.27421]
18. Ze-hua Li, Ming Cai, Yuan-shuai Liu, Pei-long Sun.  (2018)  Development of finger citron (Citrus medica L. var. sarcodactylis) essential oil loaded nanoemulsion and its antimicrobial activity.  FOOD CONTROL,  94  (317).  [PMID:] [10.1016/j.foodcont.2018.07.009]
19. Tong Qingyi, You Huijuan, Chen Xintao, Wang Kongchao, Sun Weiguang, Pei Yufeng, Zhao Xiaodan, Yuan Ming, Zhu Hucheng, Luo Zengwei, Zhang Yonghui.  (2018)  ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia.  NUCLEIC ACIDS RESEARCH,  46  (7): (3284-3297).  [PMID:29554366] [10.1093/nar/gky202]
20. Da-xia Zhang, Xian-peng Zhang, Jian Luo, Bei-xing Li, Yan Wei, Feng Liu.  (2018)  Causation Analysis and Improvement Strategy for Reduced Pendimethalin Herbicidal Activity in the Field after Encapsulation in Polyurea.  ACS Omega,  (1): (706–716).  [PMID:31457926] [10.1021/acsomega.7b01651]
21. Yan Li, Chunxia Liu, Ke Tang, Yan Chen, Kang Tian, Zhiqiang Feng, Jindong Chen.  (2018)  Novel multi‑kinase inhibitor, T03 inhibits Taxol‑resistant breast cancer.  Molecular Medicine Reports,  17  (2): (2373-2383).  [PMID:29207185] [10.3892/mmr.2017.8179]
22. Ruixue Guo, Xinbo Guo, Xiaodan Hu, Arshad Mehmood Abbasi, Lin Zhou, Tong Li, Xiong Fu, Rui Hai Liu.  (2017)  Fabrication and Optimization of Self-Microemulsions to Improve the Oral Bioavailability of Total Flavones of Hippophaë rhamnoides L.  JOURNAL OF FOOD SCIENCE,  82  (12): (2901-2909).  [PMID:29058766] [10.1111/1750-3841.13944]
23. Liu Daichun, Galvanin Federico, Yu Ying.  (2018)  Formulation Screening and Freeze-Drying Process Optimization of Ginkgolide B Lyophilized Powder for Injection.  AAPS PHARMSCITECH,  19  (2): (541-550).  [PMID:28849380] [10.1208/s12249-017-0858-2]
24. Yihui Li, Hang Hu, Qing Zhou, Yanxiao Ao, Chen Xiao, Jiangling Wan, Ying Wan, Huibi Xu, Zifu Li, Xiangliang Yang.  (2017)  α-Amylase- and Redox-Responsive Nanoparticles for Tumor-Targeted Drug Delivery.  ACS Applied Materials & Interfaces,  (22): (19215–19230).  [PMID:28513132] [10.1021/acsami.7b04066]
25. Dong Dong, Enxi Quan, Xue Yuan, Qian Xie, Zhijie Li, Baojian Wu.  (2017)  Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism.  MOLECULAR PHARMACEUTICS,  14  (9): (2864–2874).  [PMID:27983856] [10.1021/acs.molpharmaceut.6b00851]
26. Yanan Gao, Xuejing Qi, Yiping Zheng, Hongyu Ji, Linhua Wu, Nannan Zheng, Jingling Tang.  (2016)  Nanoemulsion enhances α-tocopherol succinate bioavailability in rats.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  515  (506).  [PMID:27746330] [10.1016/j.ijpharm.2016.10.026]
27. Jinli Li, Xudong Cheng, Yan Chen, Weiming He, Li Ni, Peihua Xiong, Minggang Wei.  (2016)  Vitamin E TPGS modified liposomes enhance cellular uptake and targeted delivery of luteolin: An in vivo/in vitro evaluation.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  512  (262).  [PMID:27545748] [10.1016/j.ijpharm.2016.08.037]
28. Rui Xue Guo, Xiong Fu, Jian Chen, Lin Zhou, Gu Chen.  (2016)  Preparation and Characterization of Microemulsions of Myricetin for Improving Its Antiproliferative and Antioxidative Activities and Oral Bioavailability.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  64  (32): (6286–6294).  [PMID:27455843] [10.1021/acs.jafc.6b02184]
29. Wenhua Lv, Shuangni Zhao, Hui Yu, Na Li, Vasil M. Garamus, Yiyin Chen, Peihao Yin, Rongguang Zhang, Yabin Gong, Aihua Zou.  (2016)  Brucea javanica oil-loaded nanostructure lipid carriers (BJO NLCs): Preparation, characterization and in vitro evaluation.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  504  (312).  [PMID:] [10.1016/j.colsurfa.2016.05.068]
30. Shuangni Zhao, Le Van Minh, Na Li, Vasil M. Garamus, Ulrich A. Handge, Jianwen Liu, Rongguang Zhang, Regine Willumeit-Römer, Aihua Zou.  (2016)  Doxorubicin hydrochloride-oleic acid conjugate loaded nanostructured lipid carriers for tumor specific drug release.  COLLOIDS AND SURFACES B-BIOINTERFACES,  145  (95).  [PMID:27137808] [10.1016/j.colsurfb.2016.04.027]
31. Tianpeng Zhang, Dong Dong, Danyi Lu, Shuai Wang, Baojian Wu.  (2016)  Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  501  (190).  [PMID:26850314] [10.1016/j.ijpharm.2016.01.067]
32. Kaikai Wang, Juan Wang, Wenwen Hu, Yifan Zhang, Feng Zhi, Zaigang Zhou, Jinhui Wu, Yiqiao Hu.  (2015)  Acid Denaturation Inducing Self-Assembly of Curcumin-Loaded Hemoglobin Nanoparticles.  Materials,  (12): (8701-8713).  [PMID:28793739] [10.3390/ma8125486]
33. Yiyin Chen, Xiaomin Yang, Lin Zhao, László Almásy, Vasil M. Garamus, Regine Willumeit, Aihua Zou.  (2014)  Preparation and characterization of a nanostructured lipid carrier for a poorly soluble drug.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  455  (36).  [PMID:] [10.1016/j.colsurfa.2014.04.032]
34. Sai-Ping Jiang, Sai-Nan He, Yun-Long Li, Da-Lin Feng, Xiao-Yang Lu, Yong-Zhong Du, He-Yong Yu, Fu-Qiang Hu, Hong Yuan.  (2013)  Preparation and characteristics of lipid nanoemulsion formulations loaded with doxorubicin.  International Journal of Nanomedicine,      [PMID:23990722] [10.2147/IJN.S47708]
35. Hongxing Ma,Mingjuan Chu,Kiyoshi Itagaki,Ping Xin,Xuegang Zhou,Dawei Zhang,Youzhi Wang,Jia Fu,Shiqin Sun.  (2014-12-03)  Formulation and in vitro characterization of a novel solid lipid-based drug delivery system..  Chemical & pharmaceutical bulletin,  62  ((12)): (1173-1179).  [PMID:25450625]

References

1. Xiaoqiang Zeng, Hongwu Sun, Yan Ye, Xing Luo, Dingyi Cai, Yun Yang, Ting Chen, Cun Sun, Shaotong Zhang, Hao Zeng.  (2023)  Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus (MRSA) Infection.  Jove-Journal of Visualized Experiments,    (199): (e65152).  [PMID:37677037] [10.3791/65152]
2. Wei Su, Xiantao Jiang, Ying Zhang, Chenxiang Lin, Jun'an Xiao, Peiyuan Li.  (2023)  Photothermal-driven disassembly of naphthalocyanine nano-photosensitizers for photothermal and photodynamic therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  647  (201).  [PMID:37247483] [10.1016/j.jcis.2023.05.113]
3. Yanming Wang, Zhang Chenghao, Zhaoli Wu, Xinran Cui, Jinmei Ren, Jingling Tang.  (2023)  In vivo and in vitro evaluation of pulmonary administration of itraconazole nanostructured lipid carriers for pulmonary aspergillosis.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,      [PMID:37039088] [10.1080/03639045.2023.2200533]
4. Qian-Qian Han, Peng-Fei Wu, Yi-Heng Li, Yu Cao, Jian-Guo Chen, Fang Wang.  (2022)  SVCT2–mediated ascorbic acid uptake buffers stress responses via DNA hydroxymethylation reprogramming of S100 calcium-binding protein A4 gene.  Redox Biology,  58  (102543).  [PMID:36436457] [10.1016/j.redox.2022.102543]
5. Gu Zhengqing, Xue Yuanyuan, Li Shuang, Adu-Frimpong Michael, Xu Ying, Yu Jiangnan, Xu Ximing, Zhu Yuan.  (2022)  Design, Characterization, and Evaluation of Diosmetin-Loaded Solid Self-microemulsifying Drug Delivery System Prepared by Electrospray for Improved Bioavailability.  AAPS PHARMSCITECH,  23  (4): (1-16).  [PMID:35381887] [10.1208/s12249-022-02263-3]
6. Haohui Shi, Na Liang, Jiyang Liu, Siyi Li, Xianfeng Gong, Pengfei Yan, Shaoping Sun.  (2021)  AIE-active polymeric micelles based on modified chitosan for bioimaging-guided targeted delivery and controlled release of paclitaxel.  CARBOHYDRATE POLYMERS,  269  (118327).  [PMID:34294339] [10.1016/j.carbpol.2021.118327]
7. Wenquan Huang, Yuehua Deng, Liping Ye, Qiuling Xie, Yanbin Jiang.  (2021)  Enhancing hemocompatibility and the performance of Au@silica nanoparticles by coating with cRGD functionalized zein.  Materials Science & Engineering C-Materials for Biological Applications,  125  (112064).  [PMID:33965097] [10.1016/j.msec.2021.112064]
8. Kang Sha, Qianfang Ma, Hanitrarimalala Veroniaina, Xiaole Qi, Jiayi Qin, Zhenghong Wu.  (2021)  Formulation optimization of solid self-microemulsifying pellets for enhanced oral bioavailability of curcumin.  PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY,  26  (5): (549-558).  [PMID:33688786] [10.1080/10837450.2021.1899203]
9. Wei Liu, Zehua Li, Kai Yang, Peilong Sun, Ming Cai.  (2021)  Effect of nanoemulsion loading finger citron (Citrus medica L. var. Sarcodactylis) essential oil on human gut microbiota.  Journal of Functional Foods,  77  (104336).  [PMID:] [10.1016/j.jff.2020.104336]
10. Ying Xie, Sen-Ling Feng, Chu-Tian Mai, Yan-Fang Zheng, Hui Wang, Zhong-Qiu Liu, Hua Zhou, Liang Liu.  (2021)  Suppression of up-regulated LXRα by silybin ameliorates experimental rheumatoid arthritis and abnormal lipid metabolism.  PHYTOMEDICINE,  80  (153339).  [PMID:33038868] [10.1016/j.phymed.2020.153339]
11. Ke Zhou, Yixin Zhu, Xuling Chen, Lingbing Li, Wei Xu.  (2020)  Redox- and MMP-2-sensitive drug delivery nanoparticles based on gelatin and albumin for tumor targeted delivery of paclitaxel.  Materials Science & Engineering C-Materials for Biological Applications,  114  (111006).  [PMID:32993973] [10.1016/j.msec.2020.111006]
12. Luyang Lu, Ping Yang, Tian Chen, Yanfu Shen, Qian Yao, Jun Yan.  (2020)  Changes in Biological Activities after Olive Oil, Pomegranate Seed Oil, and Grape Seed Oil were Formulated into Self-Nanoemulsifying Systems.  Journal of Oleo Science,      [PMID:31941867] [10.5650/jos.ess19255]
13. Siyu Guan, Qianqian Zhang, Jianwei Bao, Tijie Duan, Rongfeng Hu, Tori Czech, Jihui Tang.  (2020)  Phosphatidylserine targeting peptide-functionalized pH sensitive mixed micelles for enhanced anti-tumor drug delivery.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,  147  (87).  [PMID:31899369] [10.1016/j.ejpb.2019.12.012]
14. Ze-hua Li, Ming Cai, Kai Yang, Pei-long Sun.  (2019)  Kinetic study of d-limonene release from finger citron essential oil loaded nanoemulsions during simulated digestion in vitro.  Journal of Functional Foods,  58  (67).  [PMID:] [10.1016/j.jff.2019.04.056]
15. Yi Zhang, Haijie Zhao, Xiaozhen Wang, Hehan Xiao, Yanqing Guan.  (2019)  Effects of Cremophor EL/ethanol/oleinic acid/water microemulsion on human blood components and coagulation function.  COLLOIDS AND SURFACES B-BIOINTERFACES,  180  (254).  [PMID:31059983] [10.1016/j.colsurfb.2019.04.058]
16. Xu Peng, Zhou Hua, Li Ya-Zhuo, Yuan Zhong-Wen, Liu Chang-Xiao, Liu Liang, Xie Ying.  (2018)  Baicalein Enhances the Oral Bioavailability and Hepatoprotective Effects of Silybin Through the Inhibition of Efflux Transporters BCRP and MRP2.  Frontiers in Pharmacology,    [PMID:30416442] [10.3389/fphar.2018.01115]
17. Shengcai Yang, Dawei Zhang, Na Shen, Guanyi Wang, Zhaohui Tang, Xuesi Chen.  (2018)  Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species.  JOURNAL OF CELLULAR BIOCHEMISTRY,  120  (1): (634-644).  [PMID:30256439] [10.1002/jcb.27421]
18. Ze-hua Li, Ming Cai, Yuan-shuai Liu, Pei-long Sun.  (2018)  Development of finger citron (Citrus medica L. var. sarcodactylis) essential oil loaded nanoemulsion and its antimicrobial activity.  FOOD CONTROL,  94  (317).  [PMID:] [10.1016/j.foodcont.2018.07.009]
19. Tong Qingyi, You Huijuan, Chen Xintao, Wang Kongchao, Sun Weiguang, Pei Yufeng, Zhao Xiaodan, Yuan Ming, Zhu Hucheng, Luo Zengwei, Zhang Yonghui.  (2018)  ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia.  NUCLEIC ACIDS RESEARCH,  46  (7): (3284-3297).  [PMID:29554366] [10.1093/nar/gky202]
20. Da-xia Zhang, Xian-peng Zhang, Jian Luo, Bei-xing Li, Yan Wei, Feng Liu.  (2018)  Causation Analysis and Improvement Strategy for Reduced Pendimethalin Herbicidal Activity in the Field after Encapsulation in Polyurea.  ACS Omega,  (1): (706–716).  [PMID:31457926] [10.1021/acsomega.7b01651]
21. Yan Li, Chunxia Liu, Ke Tang, Yan Chen, Kang Tian, Zhiqiang Feng, Jindong Chen.  (2018)  Novel multi‑kinase inhibitor, T03 inhibits Taxol‑resistant breast cancer.  Molecular Medicine Reports,  17  (2): (2373-2383).  [PMID:29207185] [10.3892/mmr.2017.8179]
22. Ruixue Guo, Xinbo Guo, Xiaodan Hu, Arshad Mehmood Abbasi, Lin Zhou, Tong Li, Xiong Fu, Rui Hai Liu.  (2017)  Fabrication and Optimization of Self-Microemulsions to Improve the Oral Bioavailability of Total Flavones of Hippophaë rhamnoides L.  JOURNAL OF FOOD SCIENCE,  82  (12): (2901-2909).  [PMID:29058766] [10.1111/1750-3841.13944]
23. Liu Daichun, Galvanin Federico, Yu Ying.  (2018)  Formulation Screening and Freeze-Drying Process Optimization of Ginkgolide B Lyophilized Powder for Injection.  AAPS PHARMSCITECH,  19  (2): (541-550).  [PMID:28849380] [10.1208/s12249-017-0858-2]
24. Yihui Li, Hang Hu, Qing Zhou, Yanxiao Ao, Chen Xiao, Jiangling Wan, Ying Wan, Huibi Xu, Zifu Li, Xiangliang Yang.  (2017)  α-Amylase- and Redox-Responsive Nanoparticles for Tumor-Targeted Drug Delivery.  ACS Applied Materials & Interfaces,  (22): (19215–19230).  [PMID:28513132] [10.1021/acsami.7b04066]
25. Dong Dong, Enxi Quan, Xue Yuan, Qian Xie, Zhijie Li, Baojian Wu.  (2017)  Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism.  MOLECULAR PHARMACEUTICS,  14  (9): (2864–2874).  [PMID:27983856] [10.1021/acs.molpharmaceut.6b00851]
26. Yanan Gao, Xuejing Qi, Yiping Zheng, Hongyu Ji, Linhua Wu, Nannan Zheng, Jingling Tang.  (2016)  Nanoemulsion enhances α-tocopherol succinate bioavailability in rats.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  515  (506).  [PMID:27746330] [10.1016/j.ijpharm.2016.10.026]
27. Jinli Li, Xudong Cheng, Yan Chen, Weiming He, Li Ni, Peihua Xiong, Minggang Wei.  (2016)  Vitamin E TPGS modified liposomes enhance cellular uptake and targeted delivery of luteolin: An in vivo/in vitro evaluation.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  512  (262).  [PMID:27545748] [10.1016/j.ijpharm.2016.08.037]
28. Rui Xue Guo, Xiong Fu, Jian Chen, Lin Zhou, Gu Chen.  (2016)  Preparation and Characterization of Microemulsions of Myricetin for Improving Its Antiproliferative and Antioxidative Activities and Oral Bioavailability.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  64  (32): (6286–6294).  [PMID:27455843] [10.1021/acs.jafc.6b02184]
29. Wenhua Lv, Shuangni Zhao, Hui Yu, Na Li, Vasil M. Garamus, Yiyin Chen, Peihao Yin, Rongguang Zhang, Yabin Gong, Aihua Zou.  (2016)  Brucea javanica oil-loaded nanostructure lipid carriers (BJO NLCs): Preparation, characterization and in vitro evaluation.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  504  (312).  [PMID:] [10.1016/j.colsurfa.2016.05.068]
30. Shuangni Zhao, Le Van Minh, Na Li, Vasil M. Garamus, Ulrich A. Handge, Jianwen Liu, Rongguang Zhang, Regine Willumeit-Römer, Aihua Zou.  (2016)  Doxorubicin hydrochloride-oleic acid conjugate loaded nanostructured lipid carriers for tumor specific drug release.  COLLOIDS AND SURFACES B-BIOINTERFACES,  145  (95).  [PMID:27137808] [10.1016/j.colsurfb.2016.04.027]
31. Tianpeng Zhang, Dong Dong, Danyi Lu, Shuai Wang, Baojian Wu.  (2016)  Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  501  (190).  [PMID:26850314] [10.1016/j.ijpharm.2016.01.067]
32. Kaikai Wang, Juan Wang, Wenwen Hu, Yifan Zhang, Feng Zhi, Zaigang Zhou, Jinhui Wu, Yiqiao Hu.  (2015)  Acid Denaturation Inducing Self-Assembly of Curcumin-Loaded Hemoglobin Nanoparticles.  Materials,  (12): (8701-8713).  [PMID:28793739] [10.3390/ma8125486]
33. Yiyin Chen, Xiaomin Yang, Lin Zhao, László Almásy, Vasil M. Garamus, Regine Willumeit, Aihua Zou.  (2014)  Preparation and characterization of a nanostructured lipid carrier for a poorly soluble drug.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  455  (36).  [PMID:] [10.1016/j.colsurfa.2014.04.032]
34. Sai-Ping Jiang, Sai-Nan He, Yun-Long Li, Da-Lin Feng, Xiao-Yang Lu, Yong-Zhong Du, He-Yong Yu, Fu-Qiang Hu, Hong Yuan.  (2013)  Preparation and characteristics of lipid nanoemulsion formulations loaded with doxorubicin.  International Journal of Nanomedicine,      [PMID:23990722] [10.2147/IJN.S47708]
35. Hongxing Ma,Mingjuan Chu,Kiyoshi Itagaki,Ping Xin,Xuegang Zhou,Dawei Zhang,Youzhi Wang,Jia Fu,Shiqin Sun.  (2014-12-03)  Formulation and in vitro characterization of a novel solid lipid-based drug delivery system..  Chemical & pharmaceutical bulletin,  62  ((12)): (1173-1179).  [PMID:25450625]

Solution Calculators