| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| K655575-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $101.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | KR-33493 is a potent inhibitor of Fas-mediated cell death ( FAF1 ). |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | KR-33493 is a potent inhibitor of Fas-mediated cell death ( FAF1 ). In Vivo Body weight changes of both sexes are not related to KR-33493 in all doses. In rats administrated KR-33493 for 4 weeks, no test article-related changes in any treated groups of either sex are found in hematology, serum biochemistry, and urinalysis. In dogs administrated KR-33493 for 2 weeks, red blood cell count (RBC) value in males is significantly higher at the 1000 mg/kg/day dose than that of the control group (i.e., 6.96±0.323 vs. 6.12±0.418). However, the change of RBC is recovered after the end of the administration period. The dose-normalized AUC last is not significantly different between the groups, suggesting that KR-33493 is governed by linear kinetics . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:Fas |
| Canonical SMILES | C1=CC=C(C=C1)CCN2C=C(C(=N2)C(=O)O)NC(=O)CSC3=CC=C(C=C3)Br |
|---|---|
| Molecular Weight | 460.34 |
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