Kushenol E - ≥96.0%, high purity , CAS No.99119-72-9

Item Number

K647498

Grouped product items
SKU	Size	Availability	Price	Qty
K647498-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
K647498-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,050.90

Flavonoids Flavonones Phenols Polyphenols

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Basic Description

Synonyms	Kushenol E\|99119-72-9\|Flemiphilippinin D\|KushenolE\|U5JUH7PH28\|CHEMBL4579018\|(2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one\|(2S)-2-(2,4-DIHYDROXYPHENYL)-2,3-DIHYDRO-5,7-DIHYDROXY-6,8-BIS(3-METHYL-2-BUTEN-1-Y
Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC 50 of 7.7u2009µM and a K i of 9.5u2009µM, has anti-tumor activity.
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice
Product Description	Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC 50 of 7.7 µM and a K i of 9.5 µM, has anti-tumor activity. Form:Solid

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
INCHI	InChI=1S/C25H28O6/c1-13(2)5-8-17-23(29)18(9-6-14(3)4)25-22(24(17)30)20(28)12-21(31-25)16-10-7-15(26)11-19(16)27/h5-7,10-11,21,26-27,29-30H,8-9,12H2,1-4H3/t21-/m0/s1
InChi Key	ZTEYEFPSJPSRRA-NRFANRHFSA-N
Canonical SMILES	CC(=CCC1=C(C(=C2C(=C1O)C(=O)CC(O2)C3=C(C=C(C=C3)O)O)CC=C(C)C)O)C
Isomeric SMILES	CC(=CCC1=C(C(=C2C(=C1O)C(=O)C[C@H](O2)C3=C(C=C(C=C3)O)O)CC=C(C)C)O)C
PubChem CID	127234
Molecular Weight	424.5

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Basic Description