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L 012 sodium salt - ≥98%(HPLC), high purity , CAS No.143556-24-5

  • ≥98%(HPLC)
Item Number
L287250
Grouped product items
SKUSizeAvailabilityPrice Qty
L287250-1mg
1mg
In stock
$35.90
L287250-5mg
5mg
In stock
$148.90
L287250-10mg
10mg
In stock
$246.90
L287250-25mg
25mg
In stock
$555.90
L287250-50mg
50mg
In stock
$1,000.90

Chemiluminescent ROS and RNS indicator

View related series
Reactive Oxygen Species

Basic Description

SynonymsL 012 sodium salt|L012 sodium|143556-24-5|sodium 8-amino-5-chloro-4-oxo-7-phenyl-3,4-dihydropyrido[3,4-d]pyridazin-1-olate|sodium;8-amino-5-chloro-4-oxo-7-phenyl-3H-pyrido[3,4-d]pyridazin-1-olate
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsLuminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Activein vitroandin vivo.
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Product Describtion:

L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2•−) and identify Nox inhibitors.

Names and Identifiers

IUPAC Name sodium;8-amino-5-chloro-4-oxo-7-phenyl-3H-pyrido[3,4-d]pyridazin-1-olate
INCHI InChI=1S/C13H9ClN4O2.Na/c14-11-8-7(12(19)17-18-13(8)20)9(15)10(16-11)6-4-2-1-3-5-6;/h1-5H,15H2,(H,17,19)(H,18,20);/q;+1/p-1
InChi Key IGEUYSJHQQCEFP-UHFFFAOYSA-M
Canonical SMILES C1=CC=C(C=C1)C2=C(C3=C(C(=O)NN=C3[O-])C(=N2)Cl)N.[Na+]
Isomeric SMILES C1=CC=C(C=C1)C2=C(C3=C(C(=O)NN=C3[O-])C(=N2)Cl)N.[Na+]
PubChem CID 154730618
Molecular Weight 310.67

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
E2415053Certificate of AnalysisSep 14, 2023 L287250
E2416018Certificate of AnalysisSep 14, 2023 L287250
I2328082Certificate of AnalysisSep 14, 2023 L287250
I2328083Certificate of AnalysisSep 14, 2023 L287250
I2328084Certificate of AnalysisSep 14, 2023 L287250
I2328085Certificate of AnalysisSep 14, 2023 L287250
I2328086Certificate of AnalysisSep 14, 2023 L287250
I2328087Certificate of AnalysisSep 14, 2023 L287250
I2328088Certificate of AnalysisSep 14, 2023 L287250
I2328089Certificate of AnalysisSep 14, 2023 L287250
I2328090Certificate of AnalysisSep 14, 2023 L287250
I2328091Certificate of AnalysisSep 14, 2023 L287250

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 6.21, Max Conc. mM: 20; Solvent:DMSO, Max Conc. mg/mL: 31.07, Max Conc. mM: 100
SensitivityMoisture sensitive;Light sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

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Solution Calculators