L-368,899 hydrochloride - 97%, high purity , CAS No.160312-62-9

Item Number

L288722

Grouped product items
SKU	Size	Availability	Price
L288722-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
L288722-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$249.90
L288722-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$389.90
L288722-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$864.90
L288722-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,383.90
L288722-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,219.90

Potent, non-peptide oxytocin receptor antagonist

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Basic Description

Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Potent, non-peptide and orally active oxytocin receptor antagonist (IC50= 8.9 nM) that displays > 40-fold selectivity over Vasotocin V1aand V2receptors (IC50values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractionsin vitro
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent.

Names and Identifiers

IUPAC Name	(2S)-2-amino-N-[(2S)-7,7-dimethyl-1-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-2-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide;hydrochloride
INCHI	InChI=1S/C26H42N4O5S2.ClH/c1-19-7-5-6-8-22(19)29-12-14-30(15-13-29)37(34,35)18-26-11-9-20(25(26,2)3)17-23(26)28-24(31)21(27)10-16-36(4,32)33;/h5-8,20-21,23H,9-18,27H2,1-4H3,(H,28,31);1H/t20?,21-,23-,26?;/m0./s1
InChi Key	GIUFQWFJHXXXEQ-PHSYAEQHSA-N
Canonical SMILES	CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)CC34CCC(C3(C)C)CC4NC(=O)C(CCS(=O)(=O)C)N.Cl
Isomeric SMILES	CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)CC34CCC(C3(C)C)C[C@@H]4NC(=O)[C@H](CCS(=O)(=O)C)N.Cl
PubChem CID	90488775
Molecular Weight	591.23

Certificates

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12 results found

Lot Number	Certificate Type	Date	Item
I2403494	Certificate of Analysis	Jun 03, 2024	L288722
I2403495	Certificate of Analysis	Jun 03, 2024	L288722
I2403496	Certificate of Analysis	Jun 03, 2024	L288722
I2403497	Certificate of Analysis	Jun 03, 2024	L288722
I2403498	Certificate of Analysis	Jun 03, 2024	L288722
I2403499	Certificate of Analysis	Jun 03, 2024	L288722
I2403500	Certificate of Analysis	Jun 03, 2024	L288722
I2403501	Certificate of Analysis	Jun 03, 2024	L288722
I2403502	Certificate of Analysis	Jun 03, 2024	L288722
I2403503	Certificate of Analysis	Jun 03, 2024	L288722
I2403504	Certificate of Analysis	Jun 03, 2024	L288722
I2403505	Certificate of Analysis	Jun 03, 2024	L288722

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