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L-α-Aminoadipic acid - 98%, high purity , CAS No.1118-90-7
Basic Description Synonyms L-2-Aminoadipic acid|1118-90-7|(S)-2-aminohexanedioic acid|(2S)-2-aminohexanedioic acid|L-alpha-Aminoadipic acid|L-alpha-Aminoadipate|L-2-Aminoadipate|h-aad-oh|(S)-2-Aminoadipic acid|L-2-Aminohexanedioate|hexanedioic acid, 2-amino-, (2S)-|l-2-amino adipic Specifications & Purity ≥98% Shipped In Normal Product Description L-α-Aminoadipic acid, a gliotoxic analogue of glutamate, has been shown to competitively inhibit the transport protein of D-[3H]-aspartate. Experiments have reported that this compound also causes a reduction in ischemic glutamate release in murine hippocampal slices in vitro. Additional research suggests that L-α-Aminoadipic acid inhibits astrocyte culture Kynurenic acid synthesis which demonstrates the ability to modulate neuronal degeneration. L-α-Aminoadipic acid is a inhibitor of GluR and Gl Syn.
Names and Identifiers Pubchem Sid 488186685 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488186685 IUPAC Name (2S)-2-aminohexanedioic acid INCHI InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1 InChi Key OYIFNHCXNCRBQI-BYPYZUCNSA-N Canonical SMILES C(CC(C(=O)O)N)CC(=O)O Isomeric SMILES C(C[C@@H](C(=O)O)N)CC(=O)O WGK Germany 3 PubChem CID 92136 Molecular Weight 161.16 Beilstein 1724348 Reaxy-Rn 1724348
Chemical and Physical Properties Solubility Soluble in 1N HCl (50 mg/ml), and water (slightly). Specific Rotation[α] 25 ° (C=5, 6mol/L HCl) Melt Point(°C) 203-205°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 Reaxy-Rn 1724348
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E2411090
