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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L339698-5mg | 5mg | In stock | $48.90 | |
L339698-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $168.90 | |
L339698-100mg | 100mg | In stock | $472.90 |
a major component of oxidized low density lipoproteins that has been implicated in various inflammatory re
Synonyms | Lysophosphatidylcholine|Lysophosphatidylcholines|9008-30-4|1-acetyl-sn-glycero-3-phosphocholine|UNII-CQD833204Z|Lysophosphatidylcholine, soybean|CQD833204Z|[(2R)-3-acetyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate|EINECS 232-715-0|PC(2:0/0: |
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Specifications & Purity | ≥99%, Type I, powder |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR |
Mechanism of action | Activator of ASIC3;Activator of K 2P10.1;Activator of TRPC5;Activator of TRPC6;Activator of TRPV2 |
Product Description | Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels. |
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IUPAC Name | [(2R)-3-acetyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate |
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INCHI | InChI=1S/C10H22NO7P/c1-9(12)16-7-10(13)8-18-19(14,15)17-6-5-11(2,3)4/h10,13H,5-8H2,1-4H3/t10-/m1/s1 |
InChi Key | RYCNUMLMNKHWPZ-SNVBAGLBSA-N |
Canonical SMILES | CC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O |
Isomeric SMILES | CC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)O |
WGK Germany | 3 |
Alternate CAS | 9008-30-4 |
PubChem CID | 5311264 |
MeSH Entry Terms | Lysolecithin;Lysolecithins;Lysophosphatidylcholine;Lysophosphatidylcholines |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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K2321380 | Certificate of Analysis | Nov 07, 2023 | L339698 |
K2321381 | Certificate of Analysis | Nov 07, 2023 | L339698 |
K2321382 | Certificate of Analysis | Nov 07, 2023 | L339698 |
H2223376 | Certificate of Analysis | Jul 30, 2022 | L339698 |
H2223449 | Certificate of Analysis | Jul 30, 2022 | L339698 |
H2223450 | Certificate of Analysis | Jul 30, 2022 | L339698 |
WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |
Starting at $159.90
Starting at $139.90