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L-Arginine 7-amido-4- methylcoumarin dihydrochloride , CAS No.113712-08-6
a fluorogenic substrate of Cathepsin H
Basic Description Synonyms H-Arg-AMC?2HCl Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description L-Arginine 7-amido-4- methylcoumarin dihydrochloride is an excellent sensitive fluorogenic substrate of cathepsin H for the quantitative determination of activity. This chemical is also useful as a substrate for aminopeptidase B, CD13 (pepN), pepC, and Trypsin and yields a blue fluorescent solution upon cleavage.
Names and Identifiers IUPAC Name (2S)-2-amino-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide;dihydrochloride INCHI InChI=1S/C16H21N5O3.2ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);2*1H/t12-;;/m0../s1 InChi Key QMGJRBUFCDSWOX-LTCKWSDVSA-N Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)N.Cl.Cl Isomeric SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CCCN=C(N)N)N.Cl.Cl PubChem CID 2733800 Molecular Weight 404.29
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