Grouped product items

SKU

Size

Availability

Price

Qty

A104524-25g

25g

Available within 1-2 weeks(?)

$19.90

A104524-100g

100g

In stock

$71.90

A104524-250g

250g

In stock

$161.90

A104524-500g

500g

Available within 4-8 weeks(?)

$290.90

Basic Description

Synonyms	ASCORBYL PALMITATE\|137-66-6\|L-Ascorbyl 6-palmitate\|6-O-Palmitoyl-L-ascorbic acid\|L-Ascorbic acid 6-palmitate\|6-O-Palmitoylascorbic acid\|L-Ascorbic acid, 6-hexadecanoate\|(S)-2-((R)-3,4-Dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl palmitate\|L-Ascor
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	L-Ascorbyl palmitate (Asc-6P) is used along with other fatty acid ascorbates such as L-ascorbyl oleate and L-ascorbyl linoleate to protect cells and membranes from oxidative damage. Fatty acid ascorbate molecules have increased solubility in non-polar (li
Shipped In	Normal
Product Description	Product Application: L-Ascorbyl palmitate (Asc-6P) is used along with other fatty acid ascorbates such as L-ascorbyl oleate and L-ascorbyl linoleate to protect cells and membranes from oxidative damage. Fatty acid ascorbate molecules have increased solubility in non-polar (lipophilic) environments. It is applied as humectants and emollients.

Associated Targets

HSPD1 Tbio 60 kDa heat shock protein, mitochondrial 0 Activities

Discover Target: HSPD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TST Tchem Thiosulfate sulfurtransferase 0 Activities

Discover Target: TST

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AMY1A Tchem Alpha-amylase 1 0 Activities

Discover Target: AMY1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AMY2A Tclin Pancreatic alpha-amylase 0 Activities

Discover Target: AMY2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HYAL2 Tbio Hyaluronidase-2 0 Activities

Discover Target: HYAL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488201691
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488201691
IUPAC Name	[(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] hexadecanoate
INCHI	InChI=1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1
InChi Key	QAQJMLQRFWZOBN-LAUBAEHRSA-N
Canonical SMILES	CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O
Isomeric SMILES	CCCCCCCCCCCCCCCC(=O)OC[C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O
WGK Germany	1
PubChem CID	54680660
Molecular Weight	414.53
Beilstein	96552

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot Number	Certificate Type	Date	Item
G2416551	Certificate of Analysis	Apr 29, 2024	A104524
G2416552	Certificate of Analysis	Apr 29, 2024	A104524
G2416554	Certificate of Analysis	Apr 29, 2024	A104524
H2308688	Certificate of Analysis	May 24, 2023	A104524
H2308690	Certificate of Analysis	May 24, 2023	A104524
H2308691	Certificate of Analysis	May 24, 2023	A104524
H2308693	Certificate of Analysis	May 24, 2023	A104524
B2310303	Certificate of Analysis	Feb 16, 2023	A104524
B2219248	Certificate of Analysis	Feb 23, 2022	A104524
B2219306	Certificate of Analysis	Feb 23, 2022	A104524
B2219316	Certificate of Analysis	Feb 23, 2022	A104524
B2219317	Certificate of Analysis	Feb 23, 2022	A104524
E2304428	Certificate of Analysis	Feb 23, 2022	A104524

Chemical and Physical Properties

Sensitivity	Light sensitive.
Specific Rotation[α]	22.5 ° (C=1, EtOH)
Melt Point(°C)	114°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	1

Alternative Products

References

1. Qing-Xun Song,Dong-Zhi Wei,Wen-Yu Zhou,Wei-Qin Xu,Sheng-Li Yang. (2005-01-27) Enzymatic synthesis and antioxidant properties of L-ascorbyl oleate and L-ascorbyl linoleate.. Biotechnology letters, 26 ((23)): (1777-1780). [PMID:15672213]
2. Karl-Heinz Wagner,Patrick Feigl,Ibrahim Elmadfa. (2005-04-06) Ascorbyl palmitate and its synergism to tocopherols.. Forum of nutrition, 56 (347-348). [PMID:15806929]
3. Gopa Mitra,P K Mukhopadhyay,S Ayyappan. (2008-03-11) Modulation of digestive enzyme activities during ontogeny of Labeo rohita larvae fed ascorbic acid enriched zooplankton.. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 149 ((4)): (341-350). [PMID:18329933]
4. Michelle Olsher,Parkson Lee-Gau Chong. (2008-08-13) Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants.. Analytical biochemistry, 382 ((1)): (1-8). [PMID:18694720]
5. J H Han,H-M Hwang,S Min,J M Krochta. (2008-11-21) Coating of peanuts with edible whey protein film containing alpha-tocopherol and ascorbyl palmitate.. Journal of food science, 73 ((8)): (E349-E355). [PMID:19019105]
6. Kyung Mi Lee,Jung Yeon Kwon,Ki Won Lee,Hyong Joo Lee. (2008-11-26) Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway.. Mutation research, 660 ((1-2)): (51-56). [PMID:19026667]
7. Yohko Kuge,Ayato Kanda,Setsuko Hara. (2009-05-12) Pursuit of oxidation behavior for conjugated polyenoyl glycerols and establishment of their novel oxidation prevention method.. Journal of oleo science, 58 ((6)): (295-301). [PMID:19430191]
8. M M Almeida,J M P Alves,D C S Patto,C R R C Lima,J S Quenca-Guillen,M I R M Santoro,E R M Kedor-Hackmann. (2009-05-27) Determination of tocopheryl acetate and ascorbyl tetraisopalmitate in cosmetic formulations by HPLC.. International journal of cosmetic science, 31 ((6)): (445-450). [PMID:19467029]
9. Mayura Wittayasuporn,Sirirat Rengpipat,Tanapat Palaga,Pravit Asawanonda,Nattaporn Anumansirikul,Supasorn P Wanichwecharungruang. (2009-07-02) Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation.. Journal of microencapsulation, 27 ((3)): (218-225). [PMID:19566395]
10. Kazufusa Shinomiya,Heran Li,Susumu Kitanaka,Yoichiro Ito. (2010-01-05) Countercurrent Chromatographic Separation of Lipophilic Ascorbic Acid Derivatives and Extract from Kadsura Coccinea Using Hydrophobic Organic-Aqueous Two-Phase Solvent Systems.. Journal of liquid chromatography & related technologies, 32 ((16)): (2361-2371). [PMID:20046934]
11. Charlotte Jacobsen. (2010-04-15) Enrichment of foods with omega-3 fatty acids: a multidisciplinary challenge.. Annals of the New York Academy of Sciences, 1190 (141-150). [PMID:20388145]
12. P O Nnamani,A A Attama,E C Ibezim,M U Adikwu. (2010-06-18) SRMS142-based solid lipid microparticles: application in oral delivery of glibenclamide to diabetic rats.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76 ((1)): (68-74). [PMID:20554020]
13. Raju Jukanti,Gopinath Devraj,Apte S Shashank,Rambhau Devraj. (2011-01-27) Biodistribution of ascorbyl palmitate loaded doxorubicin pegylated liposomes in solid tumor bearing mice.. Journal of microencapsulation, 28 ((2)): (142-149). [PMID:21265713]
14. Lindomar A Lerin,Miriam C Feiten,Aline Richetti,Geciane Toniazzo,Helen Treichel,Marcio A Mazutti,J Vladimir Oliveira,Enrique G Oestreicher,Débora de Oliveira. (2011-01-29) Enzymatic synthesis of ascorbyl palmitate in ultrasound-assisted system: process optimization and kinetic evaluation.. Ultrasonics sonochemistry, 18 ((5)): (988-996). [PMID:21273112]
15. Dilyana Paneva,Nevena Manolova,Mariana Argirova,Iliya Rashkov. (2011-07-06) Antibacterial electrospun poly(ɛ-caprolactone)/ascorbyl palmitate nanofibrous materials.. International journal of pharmaceutics, 416 ((1)): (346-355). [PMID:21726615]
16. Luciano Benedini,Maria Laura Fanani,Bruno Maggio,Natalia Wilke,Paula Messina,Santiago Palma,Pablo Schulz. (2011-07-20) Surface phase behavior and domain topography of ascorbyl palmitate monolayers.. Langmuir : the ACS journal of surfaces and colloids, 27 ((17)): (10914-10919). [PMID:21766856]
17. Rupa R Sawant,Onkar S Vaze,Tao Wang', "Gerard G M D'Souza", 'Karen Rockwell,Keyur Gada,Ban-An Khaw,Vladimir P Torchilin. (2011-08-17) Palmitoyl ascorbate liposomes and free ascorbic acid: comparison of anticancer therapeutic effects upon parenteral administration.. Pharmaceutical research, 29 ((2)): (375-383). [PMID:21845505]
18. DeMarquis O Loyd,Sean M Lynch. (2011-08-30) Lipid-soluble vitamin C palmitate and protection of human high-density lipoprotein from hypochlorite-mediated oxidation.. International journal of cardiology, 152 ((2)): (256-257). [PMID:21872949]
19. Bente M Jensen,John Sørensen,Grith Mortensen,Martin B Sørensen,Trine K Dalsgaard. (2011-11-11) Effect of antioxidants on oxidation during the production of whey fat concentrate.. Journal of agricultural and food chemistry, 59 ((24)): (13012-13017). [PMID:22070410]
20. A Carmichael. (2012-04-28) PA and fish oil.. British dental journal, 212 ((8)): (356-357). [PMID:22538879]
21. L Capretto,S Mazzitelli,G Colombo,R Piva,L Penolazzi,R Vecchiatini,X Zhang,C Nastruzzi. (2012-08-14) Production of polymeric micelles by microfluidic technology for combined drug delivery: application to osteogenic differentiation of human periodontal ligament mesenchymal stem cells (hPDLSCs).. International journal of pharmaceutics, 440 ((2)): (195-206). [PMID:22884778]
22. Mi Kyung Kim,Ji-Soo Lee,Kwang Yup Kim,Hyeon Gyu Lee. (2012-12-19) Ascorbyl palmitate-loaded chitosan nanoparticles: characteristic and polyphenol oxidase inhibitory activity.. Colloids and surfaces. B, Biointerfaces, 103 (391-394). [PMID:23247266]
23. Mirjam Gosenca,Marija Bešter-Rogač,Mirjana Gašperlin. (2013-05-07) Lecithin based lamellar liquid crystals as a physiologically acceptable dermal delivery system for ascorbyl palmitate.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 50 ((1)): (114-122). [PMID:23643736]
24. Li Xiao,Takeki Tsutsui,Nobuhiko Miwa. (2014-06-06) The lipophilic vitamin C derivative, 6-o-palmitoylascorbate, protects human lymphocytes, preferentially over ascorbate, against X-ray-induced DNA damage, lipid peroxidation, and protein carbonylation.. Molecular and cellular biochemistry, 394 ((1-2)): (247-259). [PMID:24898782]
25. Lingyan Kong,Gregory R Ziegler. (2014-07-20) Molecular encapsulation of ascorbyl palmitate in preformed V-type starch and amylose.. Carbohydrate polymers, 111 (256-263). [PMID:25037350]
26. Marija Stojanović,Milica Carević,Mladen Mihailović,Dušan Veličković,Aleksandra Dimitrijević,Nenad Milosavić,Dejan Bezbradica. (2014-09-17) Influence of fatty acid on lipase-catalyzed synthesis of ascorbyl esters and their free radical scavenging capacity.. Biotechnology and applied biochemistry, 62 ((4)): (458-466). [PMID:25224149]
27. Mostafa Nakach,Jean-René Authelin,Tharwat Tadros,Laurence Galet,Alain Chamayou. (2014-10-04) Engineering of nano-crystalline drug suspensions: employing a physico-chemistry based stabilizer selection methodology or approach.. International journal of pharmaceutics, 476 ((1-2)): (277-288). [PMID:25278040]
28. Atikorn Panya,Waranya Temthawee,Natthaporn Phonsatta,Danai Charoensuk,Pawinee Deetae,Wonnop Visessanguan,Eric A Decker. (2015-08-15) Apolar Radical Initiated Conjugated Autoxidizable Triene (ApoCAT) Assay: Effects of Oxidant Locations on Antioxidant Capacities and Interactions.. Journal of agricultural and food chemistry, 63 ((34)): (7546-7555). [PMID:26273904]
29. Rangrong Yoksan,Jatesuda Jirawutthiwongchai,Kridsada Arpo. (2009-12-17) Encapsulation of ascorbyl palmitate in chitosan nanoparticles by oil-in-water emulsion and ionic gelation processes.. Colloids and surfaces. B, Biointerfaces, 76 ((1)): (292-297). [PMID:20004558]
30. Kunikazu Moribe,Sunao Maruyama,Yutaka Inoue,Toyofumi Suzuki,Toshiro Fukami,Kazuo Tomono,Kenjirou Higashi,Yuichi Tozuka,Keiji Yamamoto. (2009-12-17) Ascorbyl dipalmitate/PEG-lipid nanoparticles as a novel carrier for hydrophobic drugs.. International journal of pharmaceutics, 387 ((1-2)): (236-243). [PMID:20005934]
31. Mirjam Gosenca,Aleš Obreza,Slavko Pečar,Mirjana Gašperlin. (2010-09-17) A new approach for increasing ascorbyl palmitate stability by addition of non-irritant co-antioxidant.. AAPS PharmSciTech, 11 ((3)): (1485-1492). [PMID:20845090]
32. Luciano Benedini,Paula V Messina,Santiago D Palma,Daniel A Allemandi,Pablo C Schulz. (2011-10-15) The ascorbyl palmitate-polyethyleneglycol 400-water system phase behavior.. Colloids and surfaces. B, Biointerfaces, 89 (265-270). [PMID:21996464]
33. Feng-Jen Tsai,Yuan-Dai Wang,Cheng-Chi Chen,Chen Hsieh,Zhi-Jiao Cheng,Yu-Jen Wu. (2012-04-28) Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum.. Journal of photochemistry and photobiology. B, Biology, 112 (7-15). [PMID:22537778]
34. Milagro Mottola,Natalia Wilke,Luciano Benedini,Rafael Gustavo Oliveira,Maria Laura Fanani. (2013-06-29) Ascorbyl palmitate interaction with phospholipid monolayers: electrostatic and rheological preponderancy.. Biochimica et biophysica acta, 1828 ((11)): (2496-2505). [PMID:23806650]
35. Alex C M Oliveira,Matthew R Miller. (2014-05-27) Purification of Alaskan walleye pollock (Gadus chalcogrammus) and New Zealand hoki (Macruronus novaezelandiae) liver oil using short path distillation.. Nutrients, 6 ((5)): (2059-2076). [PMID:24858408]
36. Sukyeong Kim,Sangbin Han,Yeongjae Kim,Hyeon-Seop Kim,Young-Ran Gu,Donghyun Kang,Yongsik Cho,Hyeonkyeong Kim,Jeeyeon Lee,Yeyoung Seo,Moon Jong Chang,Chong Bum Chang,Seung-Baik Kang,Jin-Hong Kim. (2019-10-28) Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation.. Nature communications, 10 ((1)): (4898-4898). [PMID:31653858]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

L-Ascorbic acid 6-palmitate - 99%, high purity , CAS No.137-66-6