Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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L465016-5mg | 5mg | In stock | $517.90 | |
L465016-25mg | 25mg | In stock | $1,782.90 | |
L465016-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $6,415.90 |
Synonyms | S-Sulfocysteine|L-Cysteine S-sulfate|1637-71-4|S-Sulphocysteine|S-Sulfo-L-cysteine|Cysteine-S-sulfate|Cysteine-S-sulfonate|Cysteinyl-S-sulfonate|Cysteinyl-S-sulfonic acid|S-sulpho-L-cysteine|L-Cysteine, S-sulfo-|Cysteine-S-Sulfonic Acid|3-(sulfosulfanyl)- |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | L-Cysteine S-sulfate (LCSS) is used as an NMDA glutamatergic receptor agonist. It serves as a substrate for cystine lyase(s).Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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IUPAC Name | (2R)-2-amino-3-sulfosulfanylpropanoic acid |
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INCHI | InChI=1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1 |
InChi Key | NOKPBJYHPHHWAN-REOHCLBHSA-N |
Canonical SMILES | C(C(C(=O)O)N)SS(=O)(=O)O |
Isomeric SMILES | C([C@@H](C(=O)O)N)SS(=O)(=O)O |
PubChem CID | 115015 |
Molecular Weight | 201.22 |
Beilstein | 1726832 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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I2312411 | Certificate of Analysis | Aug 23, 2023 | L465016 |
I2312412 | Certificate of Analysis | Aug 23, 2023 | L465016 |
I2312413 | Certificate of Analysis | Aug 23, 2023 | L465016 |
I2312414 | Certificate of Analysis | Aug 23, 2023 | L465016 |
I2312415 | Certificate of Analysis | Aug 23, 2023 | L465016 |
Flash Point(°F) | Not applicable |
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Flash Point(°C) | Not applicable |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
RIDADR | NONH for all modes of transport |
1. J Dunlop,A Grieve,I Damgaard,A Schousboe,R Griffiths. (1992-09-01) Sulphur-containing excitatory amino acid-evoked Ca(2+)-independent release of D-[3H]aspartate from cultured cerebellar granule cells: the role of glutamate receptor activation coupled to reversal of the acidic amino acid plasma membrane carrier.. Neuroscience, 50 ((1)): (107-115). [PMID:1357589] |
2. F A Beemer,M Duran,S K Wadman,B P Cats. (1985-04-01) Absence of hepatic molybdenum cofactor. An inborn error of metabolism associated with lens dislocation.. Ophthalmic paediatrics and genetics, 5 ((3)): (191-195). [PMID:3877898] |
3. M Duran,G Aarsen,R H Fokkens,N M Nibbering,B P Cats,P K de Bree,S K Wadman. (1981-03-19) 2-Mercaptoethanesulfonate-cysteine disulfide excretion following the administration of 2-mercaptoethanesulfonate--a pitfall in the diagnosis of sulfite oxidase deficiency.. Clinica chimica acta; international journal of clinical chemistry, 111 ((1)): (47-53). [PMID:6784974] |
4. F Orrego,S Villanueva. (1993-10-01) The chemical nature of the main central excitatory transmitter: a critical appraisal based upon release studies and synaptic vesicle localization.. Neuroscience, 56 ((3)): (539-555). [PMID:7902967] |
5. A Gorman,R Griffiths. (1994-03-01) Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors.. Neuroscience, 59 ((2)): (299-308). [PMID:8008194] |
6. H C Winter,T Ueda. (1993-01-01) Glutamate uptake system in the presynaptic vesicle: glutamic acid analogs as inhibitors and alternate substrates.. Neurochemical research, 18 ((1)): (79-85). [PMID:8096630] |
7. G L Arnold,C L Greene,J P Stout,S I Goodman. (1993-10-01) Molybdenum cofactor deficiency.. The Journal of pediatrics, 123 ((4)): (595-598). [PMID:8410516] |
8. H Zahn,H G Gattner. (1997-01-01) Hair sulfur amino acid analysis.. EXS, 78 (239-258). [PMID:8962496] |
9. R Griffiths,C Malcolm,L Ritchie,A Frandsen,A Schousboe,M Scott,P Rumsby,C Meredith. (1997-06-15) Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.. Journal of neuroscience research, 48 ((6)): (533-542). [PMID:9210523] |
10. M P Washburn,W W Wells. (1999-04-13) Identification of the dehydroascorbic acid reductase and thioltransferase (Glutaredoxin) activities of bovine erythrocyte glutathione peroxidase.. Biochemical and biophysical research communications, 257 ((2)): (567-571). [PMID:10198252] |
11. W Xia,M Sandberg,S G Weber. (2000-03-04) Development of a liquid chromatographic method for picomole determination of S-sulfocysteine in trifluoroacetic acid extracts of neonatal rat brain.. Journal of pharmaceutical and biomedical analysis, 19 ((1-2)): (261-268). [PMID:10698587] |
12. E C Ramírez,J R Whitaker. (2000-05-04) Biochemical characterization of cystine lyase from broccoli (Brassica oleracea var. italica).. Journal of agricultural and food chemistry, 47 ((6)): (2218-2225). [PMID:10794613] |
13. Claus Jacob,Gregory I Giles,Niroshini M Giles,Helmut Sies. (2003-10-17) Sulfur and selenium: the role of oxidation state in protein structure and function.. Angewandte Chemie (International ed. in English), 42 ((39)): (4742-4758). [PMID:14562341] |
14. Mohamed S Rashed,Amal A A Saadallah,Zuhair Rahbeeni,Wafaa Eyaid,Mohamed Z Seidahmed,Saad Al-Shahwan,Mustafa A M Salih,Mohammad E Osman,Mohamed Al-Amoudi,Lujane Al-Ahaidib,Minnie Jacob. (2004-11-24) Determination of urinary S-sulphocysteine, xanthine and hypoxanthine by liquid chromatography-electrospray tandem mass spectrometry.. Biomedical chromatography : BMC, 19 ((3)): (223-230). [PMID:15558695] |
15. Vural Küçükatay,Feyza Savcioğlu,Gülay Hacioğlu,Piraye Yargiçoğlu,Aysel Ağar. (2005-02-01) Effect of sulfite on cognitive function in normal and sulfite oxidase deficient rats.. Neurotoxicology and teratology, 27 ((1)): (47-54). [PMID:15681120] |
16. Emma E Hobson,Sumesh Thomas,Patricia M Crofton,Alison D Murray,John C S Dean,David Lloyd. (2005-07-19) Isolated sulphite oxidase deficiency mimics the features of hypoxic ischaemic encephalopathy.. European journal of pediatrics, 164 ((11)): (655-659). [PMID:16025295] |
17. Wen-Hann Tan,Florian S Eichler,Sadaf Hoda,Melissa S Lee,Hagit Baris,Catherine A Hanley,P Ellen Grant,Kalpathy S Krishnamoorthy,Vivian E Shih. (2005-09-06) Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature.. Pediatrics, 116 ((3)): (757-766). [PMID:16140720] |
18. Philippa B Mills,Emma J Footitt,Serkan Ceyhan,Paula J Waters,Cornelis Jakobs,Peter T Clayton,Eduard A Struys. (2012-03-10) Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency.. Journal of inherited metabolic disease, 35 ((6)): (1031-1036). [PMID:22403017] |
19. Abdel Ali Belaidi,Guenter Schwarz. (2013-02-09) Molybdenum cofactor deficiency: metabolic link between taurine and S-sulfocysteine.. Advances in experimental medicine and biology, 776 (13-19). [PMID:23392866] |
20. Glyn B Steventon,Samera Khan,Stephen C Mitchell. (2018-06-09) Comparison of the sulfur-oxygenation of cysteine and S-carboxymethyl-l-cysteine in human hepatic cytosol and the rôle of cysteine dioxygenase.. The Journal of pharmacy and pharmacology, 70 ((8)): (1069-1077). [PMID:29882598] |
21. Jasmina Zivanovic,Emilia Kouroussis,Joshua B Kohl,Bikash Adhikari,Biljana Bursac,Sonia Schott-Roux,Dunja Petrovic,Jan Lj Miljkovic,Daniel Thomas-Lopez,Youngeun Jung,Marko Miler,Sarah Mitchell,Verica Milosevic,Jose Eduardo Gomes,Moran Benhar,Bruno Gonzalez-Zorn,Ivana Ivanovic-Burmazovic,Roberta Torregrossa,James R Mitchell,Matthew Whiteman,Guenter Schwarz,Solomon H Snyder,Bindu D Paul,Kate S Carroll,Milos R Filipovic. (2019-11-19) Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration.. Cell metabolism, 30 ((6)): (1152-1170). [PMID:31735592] |
22. H J Olverman,A W Jones,K N Mewett,J C Watkins. (1988-07-01) Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes.. Neuroscience, 26 ((1)): (17-31). [PMID:2901691] |
23. J L Johnson,K V Rajagopalan. (1995-01-01) An HPLC assay for detection of elevated urinary S-sulphocysteine, a metabolic marker of sulphite oxidase deficiency.. Journal of inherited metabolic disease, 18 ((1)): (40-47). [PMID:7623441] |
24. I Maugras,J Gosteli,E Rapp,R Nyfeler. (1995-02-01) Peptide synthesis using novel S-sulfocysteine derivatives.. International journal of peptide and protein research, 45 ((2)): (152-156). [PMID:7782163] |
25. G A Qureshi,S M Baig. (1993-02-01) Application of high performance liquid chromatography in study of sulphur amino acid metabolism in uremic patients.. Biochemistry and molecular biology international, 29 ((2)): (359-368). [PMID:8495218] |
26. K Masuda,T Kamimura,M Kanesaki,K Ishii,A Imaizumi,T Sugiyama,Y Suzuki,E Ohtsuka. (1996-01-01) Efficient production of the C-terminal domain of secretory leukoprotease inhibitor as a thrombin-cleavable fusion protein in Escherichia coli.. Protein engineering, 9 ((1)): (101-106). [PMID:9053897] |
27. W Xia,M Sandberg,S G Weber. (1998-04-01) Comparison of anion-exchange and ion-modified reversed-phase liquid chromatography for the determination of S-sulfocysteine.. Journal of chromatography. B, Biomedical sciences and applications, 705 ((2)): (251-259). [PMID:9521561] |
28. G Touati,E Rusthoven,E Depondt,C Dorche,M Duran,B Heron,D Rabier,M Russo,J M Saudubray. (2000-02-22) Dietary therapy in two patients with a mild form of sulphite oxidase deficiency. Evidence for clinical and biological improvement.. Journal of inherited metabolic disease, 23 ((1)): (45-53). [PMID:10682307] |
29. R Nahum-Levy,D Lipinski,S Shavit,M Benveniste. (2001-04-28) Desensitization of NMDA receptor channels is modulated by glutamate agonists.. Biophysical journal, 80 ((5)): (2152-2166). [PMID:11325718] |
30. Anthony R Carroll,Anna Ngo,Ronald J Quinn,Joanne Redburn,John N A Hooper. (2005-06-01) Petrosamine B, an inhibitor of the Helicobacter pylori enzyme aspartyl semialdehyde dehydrogenase from the Australian sponge Oceanapia sp.. Journal of natural products, 68 ((5)): (804-806). [PMID:15921437] |
31. Tomoya Kinumi,Yukiyasu Shimomae,Ryuichi Arakawa,Yoshiro Tatsu,Yasushi Shigeri,Noboru Yumoto,Etsuo Niki. (2005-12-31) Effective detection of peptides containing cysteine sulfonic acid using matrix-assisted laser desorption/ionization and laser desorption/ionization on porous silicon mass spectrometry.. Journal of mass spectrometry : JMS, 41 ((1)): (103-112). [PMID:16382481] |
32. Abdul-Karim Abbas,Wanlin Xia,Mattias Tranberg,Holger Wigström,Stephen G Weber,Mats Sandberg. (2007-09-04) S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity.. Neurochemical research, 33 ((2)): (301-307). [PMID:17764028] |
33. L H Ngu,B Afroze,B C Chen,O Affandi,M Y Zabedah. (2009-11-13) Molybdenum cofactor deficiency in a Malaysian child.. Singapore medical journal, 50 ((10)): (e365-e367). [PMID:19907877] |
34. Cecilia Gotor,Consolación Alvarez,M Angeles Bermúdez,Inmaculada Moreno,Irene García,Luis C Romero. (2010-08-12) Low abundance does not mean less importance in cysteine metabolism.. Plant signaling & behavior, 5 ((8)): (1028-1030). [PMID:20699647] |
35. Takeshi Nakatani,Iwao Ohtsu,Gen Nonaka,Natthawut Wiriyathanawudhiwong,Susumu Morigasaki,Hiroshi Takagi. (2012-05-23) Enhancement of thioredoxin/glutaredoxin-mediated L-cysteine synthesis from S-sulfocysteine increases L-cysteine production in Escherichia coli.. Microbial cell factories, 11 (62-62). [PMID:22607201] |
36. Elke Prade,Anne Zeck,Fabian Stiefel,Andreas Unsoeld,David Mentrup,Erik Arango Gutierrez,Ingo H Gorr. (2020-11-18) Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network.. Biotechnology and bioengineering, 118 ((3)): (1091-1104). [PMID:33200817] |