Basic Description

Synonyms	L-Ethionine\|Ethionine\|13073-35-3\|S-Ethyl-L-homocysteine\|L-Homocysteine, S-ethyl-\|(S)-2-amino-4-(ethylthio)butanoic acid\|L-S-Ethylhomocysteine\|L-2-Amino-4-(ethylthio)butyric acid\|NSC 82393\|(2S)-2-amino-4-ethylsulfanylbutanoic acid\|(+)-ethionine\|Butyric aci
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Methionine analogs that interfere with standard DNA methylation and other methylation pathways, leading to pancreatic toxicity and liver cancer. But in animal studies, it has also been shown to synchronize activity with methionine depletion to prevent met
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Discover Target: CYP2D6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Discover Target: CYP2C19

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Discover Target: CYP2C9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA2D1 Tclin Voltage-dependent calcium channel subunit alpha-2/delta-1 0 Activities

Discover Target: CACNA2D1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S)-2-amino-4-ethylsulfanylbutanoic acid
INCHI	InChI=1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChi Key	GGLZPLKKBSSKCX-YFKPBYRVSA-N
Canonical SMILES	CCSCCC(C(=O)O)N
Isomeric SMILES	CCSCC[C@@H](C(=O)O)N
WGK Germany	3
RTECS	ES6825300
PubChem CID	25674
Molecular Weight	163.24

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
E1916107	Certificate of Analysis	Mar 08, 2023	E117218
G2213281	Certificate of Analysis	May 31, 2022	E117218
G2213282	Certificate of Analysis	May 31, 2022	E117218
G2213283	Certificate of Analysis	May 31, 2022	E117218

Chemical and Physical Properties

Solubility	Aqueous Acid (Slightly), Water (Slightly)
Specific Rotation[α]	22 ° (C=1, 1mol/L HCl)
Melt Point(°C)	280°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	ES6825300
Merck Index	3738

FAQs and Articles

FAQ

DNA Damage and Repair

Categories: Technical articles

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inhibitor DNA

References

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SKU	Size	Availability	Price
E117218-100mg	100mg	In stock	$66.90
E117218-250mg	250mg	In stock	$149.90
E117218-1g	1g	In stock	$538.90

L-Ethionine - 99%, high purity , CAS No.13073-35-3