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L-Glutamine - Ultrapure BioReagent, 99.5%, high purity , CAS No.56-85-9

Item Number
L432947
Grouped product items
SKUSizeAvailabilityPrice Qty
L432947-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$119.90
L432947-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$474.90
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Basic Description

SynonymsL-glutamine | glutamine | 56-85-9 | Levoglutamide | L-(+)-Glutamine | Glutamic acid amide | Cebrogen | Stimulina | (S)-2,5-Diamino-5-oxopentanoic acid | glumin | H-Gln-OH | Levoglutamid | glutamic acid 5-amide | L-Glutamide | 2-aminoglutaramic acid | Glavamin | Miglu-P | Nutrestore | Safori
Specifications & PurityMoligand™, Ultra pure biological reagent grade, ≥99.5%
Biochemical and Physiological MechanismsL-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however
Storage TempProtected from light,Argon charged
Shipped InNormal
GradeMoligand™, Ultra pure biological reagent grade
Product Description

Gene Information

rat ... Ggt1(116568)


Application

L-Glutamine has been used in culture medium for hypothalamic neurons, spacer in isotachophoresis of serum proteins, growth requirement of various microorganisms.

Associated Targets(Human)

GPRC6A Tchem G-protein coupled receptor family C group 6 member A 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Carbonic anhydrase II 17698 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Carbonic anhydrase I 13240 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Cerebroside-sulfatase 655 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Arachidonate 15-lipoxygenase 7108 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Neutral amino acid transporter A 18 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Cytochrome P450 3A4 53859 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Homo sapiens 32628 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Flap endonuclease 1 12055 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 93046 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Bloom syndrome protein 4248 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Peripheral myelin protein 22 699 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Histone-lysine N-methyltransferase MLL 17327 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Neutral amino acid transporter B(0) 65 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Histone deacetylase 6 222 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Plasmodium falciparum 966862 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Canis familiaris 36305 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Replicase polyprotein 1ab 378 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

6-phospho-1-fructokinase 7870 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Thioredoxin reductase 1, cytoplasmic 45279 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Glutamate NMDA receptor 6467 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Monocarboxylate transporter 10 73 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Amino acid transporter 271 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Asc-type amino acid transporter 1 14 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Carbonic anhydrase-like protein, putative 25 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

SARS-CoV-2 38078 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-2,5-diamino-5-oxopentanoic acid
INCHI InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChi Key ZDXPYRJPNDTMRX-VKHMYHEASA-N
Canonical SMILES C(CC(=O)N)C(C(=O)O)N
Isomeric SMILES C(CC(=O)N)[C@@H](C(=O)O)N
WGK Germany 1
RTECS MA2275100
PubChem CID 5961
Molecular Weight 146.15
Beilstein 4491
Reaxy-Rn 1723797

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilityH2O: 0.1M at20°C, clear, colorless
SensitivityMoisture sensitive；Light sensitive
Specific Rotation[α]6.8 ° (C=4, H2O)
Melt Point(°C)185-186°C

Safety and Hazards(GHS)

WGK Germany 1
RTECS MA2275100
Reaxy-Rn 1723797
Merck Index 4471

Related Documents

 SDS

 Specification Sheet

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FAQs and Articles

FAQ
Synthesis and Metabolism of Glutamate and GABA: Core Mechanisms of Neurotransmitters
Categories: Technical articles
Tags:
Building Blocks Amino acids Vitamins GABA Metabolites Neurotransmitters Glutamate Glutamate/GABA metabolism Neural signaling pathways

Citations of This Product

1. Lixia Liu, Bingqing Liu, Yongbing Hao, Jia Wang, Xiufang Xu, Xuefang Shang.  (2024)  Theory and experiment: The synthesis and drug application of “ON-OFF-ON” fluorescent probes for copper and biothiols detection.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  239  (12): (115876).  [PMID:38039872]
2. Qiankun Quan, Xinxin Ma, Ming Li, Xi Li, Haifeng Yuan.  (2024)  Ginsenoside Rg1 promotes β‑amyloid peptide degradation through inhibition of the ERK/PPARγ phosphorylation pathway in an Alzheimer's disease neuronal model.  Experimental and Therapeutic Medicine,  27  (1): (1-13).  [PMID:38125359]
3. Ting Liu, Ling Wang, Yang Yu, Zhuo Zhang, Zelong Duan, Yawen Li, Chencan Li.  (2024)  Adenosine Triphosphatase-Stabilized ZIF-67 as Peroxidase Mimic for Rapid Detection of Glutathione.  INORGANIC CHEMISTRY COMMUNICATIONS,  159  (1): (111705).  [PMID:14612514]
4. Lvyuan Fan, Zhiyu Pan, Yilin Zhong, Juan Guo, Xu Liao, Rui Pang, Qingqiang Xu, Guozhu Ye, Yubin Su.  (2023)  L-glutamine sensitizes Gram-positive-resistant bacteria to gentamicin killing.  Microbiology Spectrum,  11  (6):   [PMID:37882580]
5. Pan Jun, Cai Youzhi, Zhang Chi, Xu Sanzhong.  (2023)  Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation.  JOURNAL OF MOLECULAR HISTOLOGY,    (1-13).  [PMID:37848748]
6. Yanan Li, Pingping Dong, Long Dai, Shaoping Wang.  (2023)  Untargeted and Targeted Metabolomics Reveal the Active Peptide of Eupolyphaga sinensis Walker against Hyperlipidemia by Modulating Imbalance in Amino Acid Metabolism.  MOLECULES,  28  (20): (7049).  [PMID:37894528]
7. Li Liu, Yu-Han Lu, Min-Dan Wang, Qun-Fei Zhao, Xiu-Ping Chen, Hang Yin, Chen-Guo Feng, Fang Zhang.  (2023)  DMMIC derivatization-assisted liquid chromatography-mass spectrometry method for metabolite profiling of the glutathione anabolic pathway in esophageal cancer tissues and cells.  Journal of Pharmaceutical Analysis,  13  (23): (1365).  [PMID:38174115]
8. Zhihong Wang, Taifeng Li, Ruisheng Li, Bo Cao, Shiyuan Wang, Xiaofei Fei, Chunyu Li, Guohui Li.  (2023)  Sijunzi Tang improves gefitinib resistance by regulating glutamine metabolism.  BIOMEDICINE & PHARMACOTHERAPY,  167  (3): (115438).  [PMID:37738796]
9. Wengan Zhang, Binjie Chen, Ruke Wang, Jing Liu, Bo Wang.  (2023)  Peroxidase-like Nanozyme Composite-based Colorimetric Determination of Glutathione and Cysteine.  ANALYTICAL LETTERS,      [PMID:]
10. Zuwei Fu, Qionghai Chen, Junwei He, Sai Li, Rui Ming, Yuan Wei, Yihui Xu, Jun Liu, Liqun Zhang.  (2023)  A synergistic effect of MXene/MWCNT enables self-healable and low percolation elastomer sensor: A combined experiment and all-atom molecular dynamics simulation.  COMPOSITES SCIENCE AND TECHNOLOGY,  242  (110155).  [PMID:]
11. Yu Zheng, Xinyi Li, Caixia Wei, Yawen Gao, Guangmei Han, Jun Zhao, Cheng Zhang, Kui Zhang, Zhongping Zhang.  (2023)  Long-Lived Phosphorescent Carbon Dots as Photosensitizers for Total Antioxidant Capacity Assay.  ANALYTICAL CHEMISTRY,  95  (23): (8914–8921).  [PMID:37246518]
12. Jia-Nan Chen, Yu-Ying Zhang, Xu-Hui Huang, Meng Dong, Xiu-Ping Dong, Da-Yong Zhou, Bei-Wei Zhu, Lei Qin.  (2023)  Integrated volatolomics and metabolomics analysis reveals the characteristic flavor formation in Chouguiyu, a traditional fermented mandarin fish of China.  FOOD CHEMISTRY,  418  (135874).  [PMID:36963134]
13. Anqi Peng, Keke Yu, Shuwei Yu, Yingying Li, Hao Zuo, Ping Li, Juan Li, Jianan Huang, Zhonghua Liu, Jian Zhao.  (2023)  Aluminum and Fluoride Stresses Altered Organic Acid and Secondary Metabolism in Tea (Camellia sinensis) Plants: Influences on Plant Tolerance, Tea Quality and Safety.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (5): (4640).  [PMID:36902071]
14. Dingding Liu, Kang Wei, Chenyu Zhang, Haoran Liu, Yang Gong, Yuanyuan Ye, Jiedan Chen, Mingzhe Yao, Liang Chen, Chunlei Ma.  (2023)  The potential effects of chlorophyll-deficient mutation and tree_age on the accumulation of amino acid components in tea plants.  FOOD CHEMISTRY,  411  (135527).  [PMID:36701915]
15. Xin Wang, Changjian Zhu, Xuerong Yan, Sijie Cheng, Yong Zhang.  (2023)  The synthesis of N-doped carbon dots for visual differentiating and detection of tetracyclines.  LUMINESCENCE,  38  (2): (188-195).  [PMID:36630153]
16. Zhang Jing, Yang Junqing, Luo Ying, Li Jiansha, Gong Tao, Huang Suqiong, Xiong Yan, Jiang Xinhui.  (2022)  Determination of 23 Amino Acids and Amines in Plasma and Cortex of C57BL/6 Mice with HPLC–FLD.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,      [PMID:36572394]
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18. Fangning Liu, Zhe Li, Ge Kang, Zhai Liu, Shicheng Zhu, Ruxue He, Chenghui Zhang, Chuanxia Chen, Yizhong Lu.  (2023)  Ratiometric sensing of α-glucosidase and its inhibitor based on MnO2 nanosheets promoted in-situ fluorescent reactions.  MICROCHEMICAL JOURNAL,  186  (108352).  [PMID:]
19. Xin Huang, Rui Wang, Yikai Wang, Changbao Chen, Shuying Liu.  (2023)  Investigation on property differences of ginseng and American ginseng by spatial metabolomics of neurochemicals with desorption electrospray ionization mass spectrometry imaging.  JOURNAL OF ETHNOPHARMACOLOGY,  303  (116006).  [PMID:36516905]
20. Lin Yuan, Lei Jiang, Ze Liu, Yingying Xiang, Fei Song, Yujiao Tu.  (2023)  Selective and sensitive simultaneous detection of tartrazine and Hg2+ based on N-doped yellow-green fluorescent carbon dots.  DYES AND PIGMENTS,  209  (110893).  [PMID:]
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22. Jie Xiang, Junyi Zhang, Shunmei Li, Ruo Yuan, Yun Xiang.  (2022)  Aptamer-based and sensitive label-free colorimetric sensing of phenylalanine via cascaded signal amplifications.  ANALYTICA CHIMICA ACTA,  1230  (340393).  [PMID:36192064]
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24. Yiyi Liu, Fangling Wu, Jiabin Wang, Ling Pu, Chuan-Fan Ding.  (2022)  Simultaneous chirality separation of amino acids and their derivative by natamycin based on mobility measurements.  ANALYTICA CHIMICA ACTA,  1227  (340298).  [PMID:36089312]
25. Wei Wang, Jiandan Chen, Zhenzeng Zhou, Shanshan Zhan, Zhiyuan Xing, Hongying Liu, Linan Zhang.  (2022)  Ultrasensitive and Selective Detection of Glutathione by Ammonium Carbamate–Gold Platinum Nanoparticles-Based Electrochemical Sensor.  Life-Basel,  12  (8): (1142).  [PMID:36013320]
26. Lei Cao, Mengyan Zhou, Jiaxi Wang, Qiang Zhu, Tingting Liu, Shushu Ding, Ding-Yi Fu.  (2022)  Gold–Silver Bimetallic Nanoclusters Protected by Glutathione S-Transferase for Colorimetric Sensing of Oxytetracycline.  ACS Applied Nano Materials,  5  (8): (11176–11184).  [PMID:]
27. Yingying Xiang, Yujiao Tu, Lei Jiang, Lin Yuan, Ze Liu, Qiang Xie, Xuequan Xiong, Fei Song.  (2022)  Orange fluorescent dual-mode nanoprobe for selective and sensitive detection of amaranth based on S,N-Doped carbon dots.  DYES AND PIGMENTS,  205  (110533).  [PMID:]
28. Jing Zhang, Jun-qing Yang, Ying Luo, Jian-sha Li, Tao Gong, Su-qiong Huang, Yan Xiong, Xin-hui Jiang.  (2022)  Determination of 23 related analytes in bone marrow fluid and hippocampus of C57BL/6 mice following cerebral ischemia–reperfusion injury by HPLC-FLD.  BIOMEDICAL CHROMATOGRAPHY,  36  (10): (e5435).  [PMID:35763335]
29. Wang Ying, Li ZhiRong, Chen RongXiang.  (2022)  Simultaneous Determination of Metabolites Related to Arginine Metabolism in Rat plasma by Hydrophilic Interaction Chromatography–Tandem Mass Spectrometry.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,  61  (3): (203-210).  [PMID:35704851]
30. Meiying Yang, Xueqing Jin, Wenna Huang, Qi Shen, Chunyan Sun.  (2022)  Humic acid induced indirect photolysis of polybrominated diphenyl ethers under visible light irradiation.  Journal of Environmental Chemical Engineering,  10  (108002).  [PMID:]
31. Wenjing Wang, Yumin He, Yunling Gao, Hongrui Gao, Lei Deng, Qingwen Gui, Zhong Cao, Yulong Yin, Zemeng Feng.  (2022)  A peptide aptamer based electrochemical amperometric sensor for sensitive L-glutamate detection.  BIOELECTROCHEMISTRY,  146  (108165).  [PMID:35623273]
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41. Yu-Cai He,Dan-Ping Zhang,Zhi-Cheng Tao,Yun Lu,Yun Ding,Feng Liu,Zheng-Zhong Zhu,Huan Rui,Gao-Wei Zheng,Xian Zhang.  (2015-02-16)  Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding L-glutamine plus glycine instead of NAD+ in β-cyclodextrin-water system..  Bioresource technology,  182  (98-102).  [PMID:25682229]
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