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L-Leucine-7-amido-4-methylcoumarin hydrochloride - ≥99% (HPLC), high purity , CAS No.62480-44-8

  • ≥99%(HPLC)
Item Number
L131532
Grouped product items
SKUSizeAvailabilityPrice Qty
L131532-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$19.90
L131532-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$79.90
L131532-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$239.90
L131532-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$479.90
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Fluorogenic leucine aminopeptidase substrate.

View related series
Coumarins Fluorescence dye

Basic Description

Synonyms[(1S)-3-Methyl-1-[(4-Methyl-2-Oxo-Chromen-7-Yl)Carbamoyl]Butyl]Ammonium;(2S)-2-Amino-4-Methyl-N-(4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl)-Pentanamide Monohydrochloride; [(1S)-3-Methyl-1-[[(4-Methyl-2-Oxo-7-Chromenyl)Amino]-Oxomethyl]Butyl]Ammonium; [(1S)-1-[(
Specifications & Purity≥99% (HPLC)
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

L-Leucine 7-amido-4-methylcoumarin hydrochloride is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released.
Leu-AMC.HCl, a fluorogenic substrate for leucine aminopeptidase

Product Properties

Excitation and Emision Rangesλex 325 nm,λem 397 nm in 0.1 M Tris pH 8.0;λex 380 nm,λem 440 nm (reaction product);λex 327 nm,λem 349 nm in pH 8.0;λex 325 nm,λem 395 nm

Names and Identifiers

IUPAC Name (2S)-2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride
INCHI InChI=1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1
InChi Key VCRXITKKWBOQRZ-ZOWNYOTGSA-N
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(C)C)N.Cl
Isomeric SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CC(C)C)N.Cl
PubChem CID 2733202
Molecular Weight 324.8

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

16 results found

Lot NumberCertificate TypeDateItem
H2217474Certificate of AnalysisJun 18, 2024 L131532
B2426095Certificate of AnalysisJan 13, 2024 L131532
B2426096Certificate of AnalysisJan 13, 2024 L131532
B2426097Certificate of AnalysisJan 13, 2024 L131532
B2426099Certificate of AnalysisJan 13, 2024 L131532
B2426100Certificate of AnalysisJan 13, 2024 L131532
B2426101Certificate of AnalysisJan 13, 2024 L131532
B2426103Certificate of AnalysisJan 13, 2024 L131532
I2313437Certificate of AnalysisAug 04, 2023 L131532
I2313438Certificate of AnalysisAug 04, 2023 L131532
I2313439Certificate of AnalysisAug 04, 2023 L131532
G2128102Certificate of AnalysisMay 10, 2023 L131532
C2328143Certificate of AnalysisJun 22, 2022 L131532
H2217420Certificate of AnalysisJun 22, 2022 L131532
H2217475Certificate of AnalysisJun 22, 2022 L131532
H2311029Certificate of AnalysisJun 22, 2022 L131532

more

Chemical and Physical Properties

SolubilitySoluble in methanol at 50mg/ml
Sensitivitylight & moisture sensitive
Melt Point(°C)283℃

Related Documents

 SDS

 Specification Sheet

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  7. L-Phenylalanine 7-amido-4-methylcoumarin, trifluoroacetate salt
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  8. L-Alanine-7-amido-4-methylcoumarin
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  9. N-CBZ-Glycyl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride - 98%, used for , CAS No. 102601-58-1, by Aladdin Scientific
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References

1. Kamalanathan M et al..  (2018)  Extracellular Enzyme Activity Profile in a Chemically Enhanced Water Accommodated Fraction of Surrogate Oil: Toward Understanding Microbial Activities After the Deepwater Horizon Oil Spill..  Front Microbiol,  9  (798).  [PMID:29740422]

Solution Calculators

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