L-Methionine-(methyl-¹³C,d₃) - ≥99 atom% ¹³C, ≥98 atom% D, ≥98% (CP), high purity , CAS No.73488-65-0

Item Number
L465458
Grouped product items
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L465458-50mg
50mg
Available within 8-12 weeks(?)
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$339.90
L465458-100mg
100mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$459.90
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Stable isotope

Basic Description

Specifications & Purity≥99 atom% ¹³C, ≥98 atom% D, ≥98% (CP)
Storage TempProtected from light
Shipped InNormal
Product Description

Description

Used in the methodology of stable isotope tagging of epitopes (SITE) for identification of virus-induced peptides in vaccine development.

Names and Identifiers

IUPAC Name (2S)-2-amino-4-(trideuterio(113C)methylsulfanyl)butanoic acid
INCHI InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i1+1D3
InChi Key FFEARJCKVFRZRR-ZIHWZSJBSA-N
Canonical SMILES [2H][13C]([2H])([2H])SCC[C@H](N)C(O)=O
Isomeric SMILES [2H][13C]([2H])([2H])SCC[C@@H](C(=O)O)N
PubChem CID 15556487
Molecular Weight 153.22

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityLight sensitive;Moisture sensitive
Specific Rotation[α][α]25/D +23.1°, c = 1 in 1 M HCl
Flash Point(°F)Not applicable
Flash Point(°C)Not applicable
Melt Point(°C)284℃ (dec.) (lit.)

Safety and Hazards(GHS)

RIDADR NONH for all modes of transport

Related Documents

References

1. Hugo D Meiring, Ernst C Soethout, Martien C M Poelen, Dennis Mooibroek, Ronald Hoogerbrugge, Hans Timmermans, Claire J Boog, Albert J R Heck, Ad P J M de Jong, Cécile A C M van Els,.  (2006-01-25)  Stable isotope tagging of epitopes: a highly selective strategy for the identification of major histocompatibility complex class I-associated peptides induced upon viral infection..  Molecular & cellular proteomics : MCP,  ((5)): ( 902-913 ).  [PMID:16432254]
2. Martin Bachman,Santiago Uribe-Lewis,Xiaoping Yang,Michael Williams,Adele Murrell,Shankar Balasubramanian.  (2014-11-21)  5-Hydroxymethylcytosine is a predominantly stable DNA modification..  Nature chemistry,  ((12)): (1049-1055).  [PMID:25411882]
3. Daniele Musiani,Jabez Bok,Enrico Massignani,Liling Wu,Tommaso Tabaglio,Marica Rosaria Ippolito,Alessandro Cuomo,Umut Ozbek,Habiba Zorgati,Umesh Ghoshdastider,Robert C Robinson,Ernesto Guccione,Tiziana Bonaldi.  (2019-04-04)  Proteomics profiling of arginine methylation defines PRMT5 substrate specificity..  Science signaling,  12  ((575)):   [PMID:30940768]
4. Valeria Spadotto,Roberto Giambruno,Enrico Massignani,Marija Mihailovich,Marianna Maniaci,Francesca Patuzzo,Francesco Ghini,Francesco Nicassio,Tiziana Bonaldi.  (2019-11-30)  PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis..  Nucleic acids research,  48  ((1)): (96-115).  [PMID:31777917]
5. Daniele Musiani,Roberto Giambruno,Enrico Massignani,Marica Rosaria Ippolito,Marianna Maniaci,Sriganesh Jammula,Daria Manganaro,Alessandro Cuomo,Luciano Nicosia,Diego Pasini,Tiziana Bonaldi.  (2020-01-30)  PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin..  Cell reports,  30  ((4)): (1208-1222).  [PMID:31995759]
6. Martin Bachman,Santiago Uribe-Lewis,Xiaoping Yang,Heather E Burgess,Mario Iurlaro,Wolf Reik,Adele Murrell,Shankar Balasubramanian.  (2015-06-23)  5-Formylcytosine can be a stable DNA modification in mammals..  Nature chemical biology,  11  ((8)): (555-557).  [PMID:26098680]

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