L-Thyroxine sodium hydrate - 98%, high purity , Thyroid hormone receptor agonist, CAS No.25416-65-3, Thyroid hormone receptor agonist

Item Number

S161194

Grouped product items
SKU	Size	Availability	Price	Qty
S161194-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90

Basic Description

Synonyms	25416-65-3\|Levothyroxine sodium\|Levothyroxine sodium monohydrate\|L-Thyroxine sodium xhydrate\|Levothyroxine sodium hydrate\|L-Thyroxine sodium hydrate\|Monosodium L-thyroxine hydrate\|31178-59-3\|CHEBI:6447\|levothroid\|synthroid\|Levothyrox\|Levaxin\|Levoxyl\|Oroxi
Specifications & Purity	≥98%
Shipped In	Normal
Action Type	AGONIST
Mechanism of action	Thyroid hormone receptor agonist
Product Description	L-Thyroxine sodium hydrate (CAS# 25416-65-3) is a useful research chemical. Its free form Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.

Names and Identifiers

IUPAC Name	sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
INCHI	InChI=1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1
InChi Key	ANMYAHDLKVNJJO-LTCKWSDVSA-M
Canonical SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.[Na+]
Isomeric SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.O.[Na+]
Alternate CAS	55-03-8；50809-32-0
PubChem CID	23667619
Molecular Weight	798.86 (anhydrous basis)

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H372:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell.

Solution Calculators

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Basic Description