Grouped product items

SKU

Size

Availability

Price

Qty

L129237-10mg

10mg

In stock

$18.90

L129237-50mg

50mg

In stock

$78.90

L129237-250mg

250mg

In stock

$355.90

L129237-1g

In stock

$1,279.90

Basic Description

Synonyms	lafutidine\|118288-08-7\|206449-93-6\|FRG-8813\|Lafutidine [INN]\|(Z)-Lafutidine\|Lafutidine [JAN]\|Lafutidine free base\|rac Lafutidine\|Lafutidine [MART.]\|Lafutidine [WHO-DD]\|Lafutidine, (+/-)-\|(Z)-2-((FURAN-2-YLMETHYL)SULFINYL)-N-(4-((4-(PIPERIDIN-1-YLMETHYL)PY
Specifications & Purity	≥99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	ANTAGONIST
Mechanism of action	Histamine H2 receptor antagonist
Note	卖完停产，不再备货
Product Description	Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.

Product Properties

ALogP	1.4

Associated Targets

CUX2 Tbio Homeobox protein cut-like 2 0 Activities

Discover Target: CUX2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNR1 Tclin Cannabinoid receptor 1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD1 Tclin D(1A) dopamine receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ESR1 Tclin Estrogen receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH3 Tclin Histamine H3 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PGR Tclin Progesterone receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Discover Target: MAOA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Discover Target: ADORA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TBXA2R Tclin Thromboxane A2 receptor 0 Activities

Discover Target: TBXA2R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Discover Target: OPRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Discover Target: OPRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MLNR Tchem Motilin receptor 0 Activities

Discover Target: MLNR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488195250
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488195250
IUPAC Name	2-(furan-2-ylmethylsulfinyl)-N-[(Z)-4-[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxybut-2-enyl]acetamide
INCHI	InChI=1S/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChi Key	KMZQAVXSMUKBPD-DJWKRKHSSA-N
Canonical SMILES	C1CCN(CC1)CC2=CC(=NC=C2)OCC=CCNC(=O)CS(=O)CC3=CC=CO3
Isomeric SMILES	C1CCN(CC1)CC2=CC(=NC=C2)OC/C=C\CNC(=O)CS(=O)CC3=CC=CO3
RTECS	AC2957000
PubChem CID	5282136
Molecular Weight	431.55

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

7 results found

Lot Number	Certificate Type	Date	Item
J1526072	Certificate of Analysis	May 10, 2023	L129237
D2320700	Certificate of Analysis	Mar 15, 2023	L129237
D2320703	Certificate of Analysis	Mar 15, 2023	L129237
D2320712	Certificate of Analysis	Mar 15, 2023	L129237
D2320713	Certificate of Analysis	Mar 15, 2023	L129237
D2320714	Certificate of Analysis	Mar 15, 2023	L129237
D2320724	Certificate of Analysis	Mar 15, 2023	L129237

Chemical and Physical Properties

Solubility	DMSO 86 mg/mL Water Ethanol 13 mg/mL
Melt Point(°C)	99 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
RTECS	AC2957000
Merck Index	5347

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Lafutidine - ≥99%, high purity , Histamine H2 receptor antagonist, CAS No.118288-08-7, Histamine H2 receptor antagonist

Basic Description

Product Properties

Associated Targets

CUX2 Tbio Homeobox protein cut-like 2 0 Activities

CNR1 Tclin Cannabinoid receptor 1 0 Activities

DRD1 Tclin D(1A) dopamine receptor 0 Activities

DRD2 Tclin D(2) dopamine receptor 0 Activities

ESR1 Tclin Estrogen receptor 0 Activities

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

NR3C1 Tclin Glucocorticoid receptor 0 Activities

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

HRH3 Tclin Histamine H3 receptor 0 Activities

HDAC6 Tclin Histone deacetylase 6 0 Activities

HRH1 Tclin Histamine H1 receptor 0 Activities

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

PGR Tclin Progesterone receptor 0 Activities

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities

DRD3 Tclin D(3) dopamine receptor 0 Activities

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

ADORA2A Tclin Adenosine receptor A2a 0 Activities

CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

AR Tclin Androgen receptor 0 Activities

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

ADORA1 Tclin Adenosine receptor A1 0 Activities

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

ADORA3 Tchem Adenosine receptor A3 0 Activities

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

TBXA2R Tclin Thromboxane A2 receptor 0 Activities

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

OPRD1 Tclin Delta-type opioid receptor 0 Activities

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

OPRM1 Tclin Mu-type opioid receptor 0 Activities

MLNR Tchem Motilin receptor 0 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

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