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Lazabemide - 98%, high purity , CAS No.103878-84-8, Inhibitor of Monoamine oxidase B

Moligand™
≥98%

CAS#: 103878-84-8
Formula: C₈H₁₀ClN₃O
Molecular Weight: 199.64
PubChem CID: 71307

Item Number

L418544

Grouped product items
SKU	Size	Availability	Price
L418544-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$35.90
L418544-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$58.90
L418544-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$132.90
L418544-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$236.90
L418544-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$426.90
L418544-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$959.90

View related series

Monoamine oxidase B Inhibitor

Basic Description

Synonyms	Lazabemide\|103878-84-8\|N-(2-aminoethyl)-5-chloropyridine-2-carboxamide\|N-(2-Aminoethyl)-5-chloropicolinamide\|Ro-19-6327\|Lazabemide hydrate\|Ro 19-6327/000\|CHEMBL279390\|2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro-\|420HD787N9\|Ro-196327\|N-(2-Aminoethyl)-
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Lazabemide (Ro 19-6327) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM), but less active against MAO-A (IC50>100 μM). High concentrations of Lazabemide have inhibitory effects on monoamine uptake, with IC50 values o
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Monoamine oxidase B
Product Description	Lazabemide is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 1 Activities

Discover Target: MAOB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Discover Target: MAOA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-(2-aminoethyl)-5-chloropyridine-2-carboxamide
INCHI	InChI=1S/C8H10ClN3O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10/h1-2,5H,3-4,10H2,(H,11,13)
InChi Key	JZXRLKWWVNUZRB-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=NC=C1Cl)C(=O)NCCN
Isomeric SMILES	C1=CC(=NC=C1Cl)C(=O)NCCN
PubChem CID	71307
Molecular Weight	199.64

CAS Registry No.

Wikipedia

PubChem CID

ChEMBL Ligand

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6 results found

Lot Number	Certificate Type	Date	Item
E23151174	Certificate of Analysis	Mar 29, 2023	L418544
E23151175	Certificate of Analysis	Mar 29, 2023	L418544
E23151178	Certificate of Analysis	Mar 29, 2023	L418544
E2315257	Certificate of Analysis	Mar 29, 2023	L418544
E2315258	Certificate of Analysis	Mar 29, 2023	L418544
E2315276	Certificate of Analysis	Mar 29, 2023	L418544

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