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LCL521 - 10mM in DMSO, high purity , CAS No.1226851-11-1(DMSO)

  • 10mM in DMSO
Item Number
L654945
Grouped product items
SKUSizeAvailabilityPrice Qty
L654945-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$456.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

LCL521 is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase )

In Vitro

LCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:ACDase, ASMase

Names and Identifiers

Canonical SMILES CCCCCCCCCCCCCC(=O)NC(COC(=O)CN(C)C)C(C1=CC=C(C=C1)[N+](=O)[O-])OC(=O)CN(C)C
Molecular Weight 592.77

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Solution Calculators