LDC7559 - 99%, high purity , CAS No.2407782-01-6

Item Number

L646958

Grouped product items
SKU	Size	Availability	Price
L646958-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$90.90
L646958-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
L646958-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$400.90
L646958-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,350.90

View related series

Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages In Vitro LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells. ?\nLDC7559 functions directly through blocking the activity of the GSDMD NT domain, rather than interfering with the activation and cleavage process. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Gasdermin D

Names and Identifiers

IUPAC Name	N-[2-(2-methoxyphenyl)-4,10-dihydropyrazolo[5,1-c][1,4]benzoxazepin-7-yl]acetamide
INCHI	InChI=1S/C20H19N3O3/c1-13(24)21-15-8-7-14-11-23-16(12-26-20(14)9-15)10-18(22-23)17-5-3-4-6-19(17)25-2/h3-10H,11-12H2,1-2H3,(H,21,24)
InChi Key	IFOIINXSFCQLOV-UHFFFAOYSA-N
Canonical SMILES	CC(=O)NC1=CC2=C(CN3C(=CC(=N3)C4=CC=CC=C4OC)CO2)C=C1
Isomeric SMILES	CC(=O)NC1=CC2=C(CN3C(=CC(=N3)C4=CC=CC=C4OC)CO2)C=C1
PubChem CID	138319675
Molecular Weight	349.38

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description