Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC 50 s o
Appearance:Solid
IC50& Target:Cereblon
Biological Activity:Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC 50 s o
Names and Identifiers
Canonical SMILES
O=C(C(N(CC1=C2C=CC=C1CCCCN)C2=O)CC3)NC3=O.Cl
Molecular Weight
351.83
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
Solubility
DMSO : 130 mg/mL (369.50 mM; Need ultrasonic) H2O : 100 mg/mL (284.23 mM; Need ultrasonic)