Skip to the beginning of the images gallery

[Leu5]-Enkephalin - 98%, high purity , CAS No.58822-25-6, Agonist of δ receptor;Agonist of κ receptor;Agonist of μ receptor

Moligand™
≥98%

CAS#: 58822-25-6
Formula: C₂₈H₃₇N₅O₇
Molecular Weight: 555.63
PubChem CID: 461776

Item Number

L304070

Grouped product items
SKU	Size	Availability	Price
L304070-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$58.90
L304070-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$117.90
L304070-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$424.90

Opioid peptide and potent δ and μ-receptor agonist

View related series

δ receptor Agonist κ receptor Agonist μ receptor Agonist

Basic Description

Synonyms	Leu-enkephalin\|[Leu5]-Enkephalin\|leucine enkephalin\|58822-25-6\|Enkephalin\|Tyr-Gly-Gly-Phe-Leu\|Enkephalins\|Enkephalin L\|Leucyl-enkephalin\|[Leu]enkephalin\|Leucine-enkephalin\|ENKEPHALIN, LEUCINE\|H-Tyr-Gly-Gly-Phe-Leu-OH\|[5-Leucine]Enkephalin\|Leu5-Enkephalin\|
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of δ receptor;Agonist of κ receptor;Agonist of μ receptor
Product Description	Product Describtion: [Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

Associated Targets

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Discover Target: OPRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Discover Target: OPRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
INCHI	InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1
InChi Key	URLZCHNOLZSCCA-VABKMULXSA-N
Canonical SMILES	CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N
Isomeric SMILES	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)N
PubChem CID	461776
Molecular Weight	555.63

PubChem CID

3903

CAS Registry No.

58822-25-6

Wikipedia

Leu-enkephalin

UniProtKB

P01210, P22005, P04094

BindingDB Ligand

50016831

ChEMBL Ligand

CHEMBL15038

Ensembl Gene

ENSG00000181195, ENSMUSG00000045573, ENSRNOG00000008943

GPCRdb Ligand

[Leu]enkephalin

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
G23051116	Certificate of Analysis	Jun 13, 2023	L304070
G23051118	Certificate of Analysis	Jun 13, 2023	L304070
G23051120	Certificate of Analysis	Jun 13, 2023	L304070

Solubility

Soluble in water (1 mg/ml ).

Sensitivity

Moisture sensitive

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.