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Leukotriene C4 - ≥97%，A solution in ethanol, high purity , CAS No.72025-60-6, Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor;Agonist of GPR17

Moligand™
≥97%
A solution in ethanol

CAS#: 72025-60-6
Formula: C₃₀H₄₇N₃O₉S
Molecular Weight: 625.77
PubChem CID: 5280493

Item Number

L275222

Grouped product items
SKU	Size	Availability	Price	Qty
L275222-25μg	25μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,133.90
L275222-50μg	50μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,875.90

Potent leukotriene C 4 receptor agonist

View related series

CysLT1 receptor Agonist CysLT2 receptor Agonist GPR17 Agonist

Basic Description

Synonyms	leukotriene C4\|LTC4\|72025-60-6\|Leukotriene C\|Leukotriene C1\|LTC (sub 4)\|Leucotriene C4\|LTC4 (Leukotriene C4)\|5S,6R-Ltc(sub 4)\|LEUKOTRIENEC4\|CHEBI:16978\|2CU6TT9V48\|CHEMBL451509\|5S-hydroxy,6R-(S-glutathionyl),7E,9E,11Z,14Z-eicosatetraenoic acid\|(5S,6R,7E,9E
Specifications & Purity	Moligand™, ≥97%, A solution in ethanol
Biochemical and Physiological Mechanisms	Potent leukotriene C 4 receptor agonist (EC 50 = 300 nM). Lipid derivative of arachidonic acid and smooth muscle contractant (EC 50 = 11 nM). Causes coronary and renal vasoconstriction in vivo .
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor;Agonist of GPR17
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -80°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor 1 Activities

Discover Target: GPR17

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RGS4 Tchem Regulator of G-protein signaling 4 0 Activities

Discover Target: RGS4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYSLTR2 Tchem Cysteinyl leukotriene receptor 2 2 Activities

Discover Target: CYSLTR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 1 Activities

Discover Target: CYSLTR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
INCHI	InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,12-11+,16-13+/t22-,23-,24-,25+/m0/s1
InChi Key	GWNVDXQDILPJIG-NXOLIXFESA-N
Canonical SMILES	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
Isomeric SMILES	CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
PubChem CID	5280493
Molecular Weight	625.77

Wikipedia

ChEBI

CAS Registry No.

PubChem CID

ChEMBL Ligand

RCSB PDB Ligand

GPCRdb Ligand

LTC₄

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
G23051219	Certificate of Analysis	Apr 07, 2024	L275222
K2208533	Certificate of Analysis	Aug 14, 2023	L275222
K2208521	Certificate of Analysis	Aug 29, 2022	L275222

Solubility

Supplied in methanol/ammonium acetate buffer, 65:35, pH5.6 (50 µg/ml)

Sensitivity

Light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H350:May cause cancer
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice.

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