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Leupeptin - Ultra Pure Grade, high purity , CAS No.103476-89-7

2 Citations
Item Number
L274378
Grouped product items
SKUSizeAvailabilityPrice Qty
L274378-5mg
5mg
In stock
$255.90
L274378-25mg
25mg
In stock
$832.90
L274378-100mg
100mg
In stock
$2,175.90
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Anti-infection Cathepsin Metabolic Enzyme/Protease Ser/Thr Protease Virus Protease

Basic Description

SynonymsN-acetyl-L-leucyl-N-[(2S)-5-carbamimidamido-1-oxopentan-2-yl]-L-leucinamide sulfate (2:1) | A903394 | L-Leucinamide, N-acetyl-L-leucyl-N-((1S)-4-((aminoiminomethyl)amino)-1-formylbutyl)-, sulfate (2:1) | bis{N-acetyl-L-leucyl-N-[(2S)-5-{[azaniumyl(imino)m
Specifications & PurityEnzymoPure™, SuperPure grade
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeSuperPure grade, EnzymoPure™
Product Description

A reversible inhibitor of cysteine proteases and serine proteases resembling trypsin Reversible inhibitor Ultra pure grade Inhibits trypsin, plasmin, papain, kallikrein, thrombin and cathepsin A and B.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488192406
IUPAC Name (2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide;sulfuric acid
INCHI InChI=1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
InChi Key CIPMKIHUGVGQTG-VFFZMTJFSA-N
Canonical SMILES CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C.CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C.OS(=O)(=O)O
Isomeric SMILES CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.OS(=O)(=O)O
PubChem CID 2733491
Molecular Weight 475.59

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
H2416267Certificate of AnalysisAug 07, 2024 L274378
H2416015Certificate of AnalysisAug 07, 2024 L274378
H2416014Certificate of AnalysisAug 07, 2024 L274378
H2416013Certificate of AnalysisAug 07, 2024 L274378
G2425728Certificate of AnalysisJul 19, 2024 L274378
G2422580Certificate of AnalysisJul 12, 2024 L274378
G2419542Certificate of AnalysisJul 12, 2024 L274378
D2419007Certificate of AnalysisApr 17, 2024 L274378
D2419009Certificate of AnalysisApr 17, 2024 L274378
D2419008Certificate of AnalysisApr 17, 2024 L274378
D2419004Certificate of AnalysisApr 17, 2024 L274378
B2311873Certificate of AnalysisApr 11, 2024 L274378
D2412108Certificate of AnalysisApr 01, 2024 L274378
D2412107Certificate of AnalysisApr 01, 2024 L274378
B2311880Certificate of AnalysisFeb 01, 2024 L274378
A2403416Certificate of AnalysisDec 16, 2023 L274378
A2403434Certificate of AnalysisDec 16, 2023 L274378
A2403415Certificate of AnalysisDec 16, 2023 L274378
B2311872Certificate of AnalysisNov 17, 2023 L274378
B2311864Certificate of AnalysisNov 17, 2023 L274378
G23121414Certificate of AnalysisJun 17, 2023 L274378
G2312537Certificate of AnalysisJun 17, 2023 L274378
G2312544Certificate of AnalysisJun 17, 2023 L274378
G2312547Certificate of AnalysisJun 17, 2023 L274378
G2312551Certificate of AnalysisJun 17, 2023 L274378
B2311882Certificate of AnalysisNov 24, 2022 L274378
C2209234Certificate of AnalysisNov 26, 2021 L274378
C2209704Certificate of AnalysisNov 26, 2021 L274378
C2209705Certificate of AnalysisNov 26, 2021 L274378

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Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H312:Harmful in contact with skin

H332:Harmful if inhaled

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Leupeptin - 10mM in DMSO, used for , CAS No. 103476-89-7, by Aladdin Scientific
    Leupeptin

    Starting at $52.90

FAQs and Articles

FAQ
Chromatin preparation from tissues for chromatin immunoprecipitation (ChIP)
Categories: Protocols
Tags:
Electrophoresis ChIP Lysis buffer Aprotinin
BN-PAGE Protocol
Categories: Protocols
Tags:
Western blotting Natural polypropylene gel electrophoresis Non-denaturating gel electrophoresis BN-PAGE Coomasil brilliant blue Protein complex Horseradish peroxidase Alkaline phosphatase

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Jing Jin, Qiao‑Yun Hu, Wen‑Wen Xu, Wen‑Jia Zhu, Bei Liu, Jing Liu, Wei Wang, Hui‑Fang Zhou.  (2019)  Tanshinone IIA attenuates estradiol‑induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary.  Experimental and Therapeutic Medicine,  17  (5): (3501-3508).  [PMID:30988730] [10.3892/etm.2019.7352]
2. Yunhua Zhang, Jinyun Ji, Xiao Zhao, Ruoheng Jin, Jianhong Li, Hu Wan.  (2017)  Expression, purification and enzymatic properties of a β-N-acetylhexosaminidase from brown planthopper, Nilaparvata lugens.  JOURNAL OF ASIA-PACIFIC ENTOMOLOGY,  20  (1340).  [PMID:] [10.1016/j.aspen.2017.10.005]

References

1. Jing Jin, Qiao‑Yun Hu, Wen‑Wen Xu, Wen‑Jia Zhu, Bei Liu, Jing Liu, Wei Wang, Hui‑Fang Zhou.  (2019)  Tanshinone IIA attenuates estradiol‑induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary.  Experimental and Therapeutic Medicine,  17  (5): (3501-3508).  [PMID:30988730] [10.3892/etm.2019.7352]
2. Yunhua Zhang, Jinyun Ji, Xiao Zhao, Ruoheng Jin, Jianhong Li, Hu Wan.  (2017)  Expression, purification and enzymatic properties of a β-N-acetylhexosaminidase from brown planthopper, Nilaparvata lugens.  JOURNAL OF ASIA-PACIFIC ENTOMOLOGY,  20  (1340).  [PMID:] [10.1016/j.aspen.2017.10.005]

Solution Calculators

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