Click Here for 5% Off Your First Aladdin Purchase!

Levetiracetam - ≥99%, high purity , Voltage-gated N-type calcium channel alpha-1B subunit blocker, CAS No.102767-28-2, Voltage-gated N-type calcium channel alpha-1B subunit blocker

  • Moligand™
  • ≥99%
Item Number
L129699
Grouped product items
SKUSizeAvailabilityPrice Qty
L129699-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$12.90
L129699-1g
1g
In stock
$38.90
L129699-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$112.90
L129699-25g
25g
In stock
$504.90
L129699-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,816.90

Potent anti-epileptic; binds to SV2A

Basic Description

SynonymsLevetiracetam|102767-28-2|Keppra|(S)-2-(2-Oxopyrrolidin-1-yl)butanamide|Keppra XR|(2S)-2-(2-oxopyrrolidin-1-yl)butanamide|ucb L059|UCB-L 059|matever|Levetiracetame|Levetiracetamum|Levroxa|Spritam|UCB-L059|Elepsia|Levipil|(S)-alpha-Ethyl-2-oxo-1-pyrrolidin
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsLevetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firin
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR, MODULATOR
Mechanism of actionVoltage-gated N-type calcium channel alpha-1B subunit blocker
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Levetiracetam is an antiepileptic which displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange.
A compound which inhibits burst firing without affecting normal neuronal excitability

Product Properties

ALogP-0.3

Names and Identifiers

IUPAC Name (2S)-2-(2-oxopyrrolidin-1-yl)butanamide
INCHI InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
InChi Key HPHUVLMMVZITSG-LURJTMIESA-N
Canonical SMILES CCC(C(=O)N)N1CCCC1=O
Isomeric SMILES CC[C@@H](C(=O)N)N1CCCC1=O
WGK Germany 3
RTECS UX9656166
PubChem CID 5284583
Molecular Weight 170.21
Reaxy-Rn 8407472

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

17 results found

Lot NumberCertificate TypeDateItem
B1528010Certificate of AnalysisJun 15, 2024 L129699
F2425345Certificate of AnalysisMay 06, 2024 L129699
F2425344Certificate of AnalysisMay 06, 2024 L129699
F2425343Certificate of AnalysisMay 06, 2024 L129699
F2425342Certificate of AnalysisMay 06, 2024 L129699
F2425341Certificate of AnalysisMay 06, 2024 L129699
F2425339Certificate of AnalysisMay 06, 2024 L129699
F2425340Certificate of AnalysisMay 06, 2024 L129699
K1710001Certificate of AnalysisMay 10, 2023 L129699
C2314304Certificate of AnalysisJan 21, 2022 L129699
C2314301Certificate of AnalysisJan 21, 2022 L129699
C2314294Certificate of AnalysisJan 21, 2022 L129699
C2202111Certificate of AnalysisJan 21, 2022 L129699
C2202110Certificate of AnalysisJan 21, 2022 L129699
F2426249Certificate of AnalysisJan 21, 2022 L129699
H2325045Certificate of AnalysisJan 21, 2022 L129699
C2202109Certificate of AnalysisJan 21, 2022 L129699

more

Chemical and Physical Properties

SolubilitySoluble in water (34 mg/ml at 25 °C), DMSO (34 mg/ml at 25 °C), and ethanol (34 mg/ml at 25 °C).
Specific Rotation[α]-88° (C=1,Acetone)
Melt Point(°C)118 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS UX9656166
Reaxy-Rn 8407472

Related Documents

Solution Calculators