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Levofloxacin - 98.0-102.0% anhydrous basis (HPLC), high purity , CAS No.100986-85-4

111 Citations
Item Number
L473790
Grouped product items
SKUSizeAvailabilityPrice Qty
L473790-10mg
10mg
In stock
$23.90
L473790-1g
1g
In stock
$102.90
L473790-10g
10g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$228.90
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Basic Description

Synonyms1-bromo-2-trifluoromethyl benzene | o,.alpha.,.alpha.,.alpha.-Tetrafluorotoluene | GTPL10911 | KBio2_002199 | Levofloxacinum [INN-Latin] | MP 376 | 1-Fluoro-3-nitrobenzene, purum, >=97.0% (GC) | MLS001423977 | SPBio_001891 | (-)-Ofloxacin | LEVOFLOXACIN |
Specifications & PurityMoligand™, anhydrous, ≥98%
Gradeanhydrous, Moligand™
Product Description

Description

Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Antibiotic against bacterial respiratory tract infections.

Names and Identifiers

IUPAC Name (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
INCHI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
InChi Key GSDSWSVVBLHKDQ-JTQLQIEISA-N
Canonical SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
Isomeric SMILES C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
RTECS UU8815550
PubChem CID 149096
Molecular Weight 361.37
Reaxy-Rn 5385660

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
I2320578Certificate of AnalysisSep 22, 2023 L473790
I2320588Certificate of AnalysisSep 22, 2023 L473790
I2320589Certificate of AnalysisSep 22, 2023 L473790

Chemical and Physical Properties

Specific Rotation[α]-66° (C=5,CHCl3)
Melt Point(°C)224 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

H361:Suspected of damaging fertility or the unborn child

H362:May cause harm to breast-fed children

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

RTECS UU8815550
Reaxy-Rn 5385660
Merck Index 6771

Related Documents

 SDS

 Specification Sheet

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Zihao Yang, Qiang An, Shuman Deng, Bohan Xu, Zheng Li, Shian Deng, Bin Zhao, Zhihong Ye.  (2023)  Efficient activation of peroxydisulfate by modified red mud biochar derived from waste corn straw for levofloxacin degradation: Efficiencies and mechanisms.  Journal of Environmental Chemical Engineering,  11  (27): (111609).  [PMID:19558367] [10.1016/j.jece.2023.111609]
2. Ben-Qing Huang, Hong-Guang Cui, Tian-Yun Feng, Cai-Ling Yuan, Ai-Lian Chang, Ming-Lu Shao, Chi-Fan Zhu.  (2024)  Thin film composite polyamide nanofiltration membranes with interlayer constructed with core-shell structured polystyrene-polyacrylamide nanospheres for antibiotics separation.  Journal of Water Process Engineering,  57  (23): (104550).  [PMID:8570614] [10.1016/j.jwpe.2023.104550]
3. Wenqing Yu, Fanming Meng, Hainan Wei, Han Zhang, Sheng Yao.  (2024)  Construction of double Z-scheme Ag3PO4/MOF-In2S3/Bi2S3 heterojunction by micro-Ag bridges for photocatalytic degradation of levofloxacin.  APPLIED SURFACE SCIENCE,  648  (159010).  [PMID:12036302] [10.1016/j.apsusc.2023.159010]
4. Xin Zhong, Meihuan Ji, Wenxin Wu, Caicai Lu, Wenping Liu, Fubin Jiang.  (2024)  Enhanced Degradation of Levofloxacin through Visible-Light-Driven Peroxymonosulfate Activation over CuInS2/g-C3N4 Heterojunctions.  Nanomaterials,  14  (1): (74).  [PMID:38202529] [10.3390/nano14010074]
5. Shanguo Zhang, Tianyi Jiang, Fang Han, Liangyu Cao, Ming Li, Zhenyou Ge, Haoxiu Sun, Hao Wu, Wenlong Wu, Nannan Zhou, Muhammad Luqman Akhtar, Hongyuan Jiang.  (2024)  A wearable self-powered microneedle system based on conductive drugs for infected wound healing: A new electrical stimulation delivery strategy.  CHEMICAL ENGINEERING JOURNAL,  480  (148347).  [PMID:] [10.1016/j.cej.2023.148347]
6. Yanling Liu, Qihang Cen, Kaiming Fan, Airan Hu, Xu Yuan, Shengji Xia.  (2024)  Enhancing nanofiltration membrane selectivity between mineral salts and organic pollutants by sulfonic acid functionalization for drinking water treatment.  JOURNAL OF MEMBRANE SCIENCE,  693  (122358).  [PMID:] [10.1016/j.memsci.2023.122358]
7. Aiyuan Jia, Fangyuan Zhang, Yongsheng Zhao, Zhi Liu, Lu Xin, Mei Hong, Yangxue Li.  (2024)  Facile fabrication of shapeable three-component hydrogen-bonded covalent-organic aerogel as permeable reactive barrier material for efficient in-situ fluoroquinolone contaminated groundwater remediation.  SEPARATION AND PURIFICATION TECHNOLOGY,  334  (126037).  [PMID:] [10.1016/j.seppur.2023.126037]
8. Manlu Cheng, Xingyu Long, Ping Song, Zenghui Diao, Gang Song, Diyun Chen, Lingjun Kong.  (2024)  Co-catalytic of aluminosilicate stabilized cobalt for peroxymonosulfate activation to degrade levofloxacin.  CHEMICAL ENGINEERING JOURNAL,  480  (147885).  [PMID:] [10.1016/j.cej.2023.147885]
9. Samreen Sadiq, Iltaf Khan, Muhammad Humayun, Ping Wu, Abbas Khan, Sohail Khan, Aftab Khan, Shoaib Khan, Amal Faleh Alanazi, Mohamed Bououdina.  (2023)  Synthesis of Metal–Organic Framework-Based ZIF-8@ZIF-67 Nanocomposites for Antibiotic Decomposition and Antibacterial Activities.  ACS Omega,  8  (51): (49244–49258).  [PMID:38162750] [10.1021/acsomega.3c07606]
10. Yanzhuo Zhang, Yutai Sun, Rui He, Jing Zhao, Jiqin Wang, Tonghuan Yu, Xiaozhuan Zhang, Alexandr V. Bildyukevich.  (2024)  Effects of excess sludge composting process, environmentally persistent free radicals, and microplastics on antibiotics degradation efficiency of aging biochar.  BIORESOURCE TECHNOLOGY,  393  (15): (130070).  [PMID:37984667] [10.1016/j.biortech.2023.130070]
11. Guangli Li, Xiaoman Qi, Jingtao Wu, Xuan Wan, Tianyu Wang, Ying Liu, Yuwei Chen, Yonghui Xia.  (2024)  Highly stable electrochemical sensing platform for the selective determination of pefloxacin in food samples based on a molecularly imprinted-polymer-coated gold nanoparticle/black phosphorus nanocomposite.  FOOD CHEMISTRY,  436  (137753).  [PMID:37862994] [10.1016/j.foodchem.2023.137753]
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13. Ligui Wu, Qiaofeng Wu, Jingcheng Xu, Lingling Rong, Xiaoli Yu, Chen Cai, Xiangfeng Huang, Xiaoming Zou.  (2023)  Responses of antibiotic resistance genes in the enhanced biological phosphorus removal system under various antibiotics: Mechanisms and implications.  SCIENCE OF THE TOTAL ENVIRONMENT,  905  (167247).  [PMID:37739079] [10.1016/j.scitotenv.2023.167247]
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17. Shengzhe Wang, Hongxia Lv, Chengyu Jin, Yu Wang, Huangzhao Wei, Chenglin Sun, Lian Yu, Lei Ma, Xiangnan Li, Xiaowei Liu.  (2023)  Electrocatalytic degradation of levofloxacin wastewater by Ru-Ti-Ni/CNT electrodes.  CATALYSIS COMMUNICATIONS,  182  (106756).  [PMID:] [10.1016/j.catcom.2023.106756]
18. Jiawen Xu, Xiumin Shi, Mingyue Yi, Yanze Chi, Shuang Guo, Zhu Mao, Bing Zhao, Young Mee Jung.  (2023)  Improved charge-transfer enhancement by codoping Mg/Zn into ZrO2 for quinolone antibiotic drug determination.  APPLIED SURFACE SCIENCE,  639  (158256).  [PMID:] [10.1016/j.apsusc.2023.158256]
19. Sun Lei, Guo Hao, Liu Bingqing, Pan Zhilan, Wu Ning, Zhang Hao, Yang Wu.  (2023)  Ultrasensitive levofloxacin electrochemical biosensor based on semiconducting covalent organic framework/poly-L-cysteine/triangular Ag nanoplates modified glassy carbon electrode.  MICROCHIMICA ACTA,  190  (9): (1-10).  [PMID:37555996] [10.1007/s00604-023-05866-0]
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22. Chen Jiuyan, Zhang Qiang, Zhu Yuwei, Zhang Mengli, Zhu Yutong, Farooq Usman, Lu Taotao, Qi Zhichong, Chen Weifeng.  (2023)  Adsorption of fluoroquinolone antibiotics onto ferrihydrite under different anionic surfactants and solution pH.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (32): (78229-78242).  [PMID:37269523] [10.1007/s11356-023-28059-x]
23. Hang Lv, Yuandong Huo, Manlu Cheng, Zenghui Diao, Gang Song, Diyun Chen, Lingjun Kong.  (2023)  High yielded Co–C derived from polyester-Cobalt carbothermal reduction for efficient activation of peroxymonosulfate to degrade levofloxacin.  CHEMOSPHERE,  335  (139020).  [PMID:37247677] [10.1016/j.chemosphere.2023.139020]
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35. Wei Liu, Jin Zhang, Qun Kang, Hongbing Chen, Ru Feng.  (2023)  Enhanced photocatalytic degradation performance of In2O3/g-C3N4 composites by coupling with H2O2.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  252  (114611).  [PMID:36753972] [10.1016/j.ecoenv.2023.114611]
36. Meilan Pan, Shuang-yin Tang-hu, Chenhao Ni, Haihua Chen, Bingjun Pan.  (2023)  Constructing Ti(III)-laden TiO2 nanotube arrays for electrochemical defluorination of levofloxacin.  Journal of Environmental Chemical Engineering,  11  (109392).  [PMID:] [10.1016/j.jece.2023.109392]
37. Cao Fang, Changsheng Shao, Shenhao Wang, Yahui Wu, Chao Liu, Qing Huang.  (2023)  Simultaneous removal of levofloxacin and sulfadiazine in water by dielectric barrier discharge (DBD) plasma: Enhanced performance and degradation mechanism.  PROCESS SAFETY AND ENVIRONMENTAL PROTECTION,  171  (459).  [PMID:] [10.1016/j.psep.2023.01.040]
38. Jingwei Yan, Lin Gong, Senyou Chai, Cong Guo, Wei Zhang, Hongyou Wan.  (2023)  ZIF-67 loaded lotus leaf-derived biochar for efficient peroxymonosulfate activation for sustained levofloxacin degradation.  CHEMICAL ENGINEERING JOURNAL,  458  (141456).  [PMID:] [10.1016/j.cej.2023.141456]
39. Lanlan Liang, Peike Cao, Xin Qin, Shuai Wu, Haokun Bai, Shuo Chen, Hongtao Yu, Yan Su, Xie Quan.  (2023)  Oxygen vacancies-driven nonradical oxidation pathway of catalytic ozonation for efficient water decontamination.  APPLIED CATALYSIS B-ENVIRONMENTAL,  325  (122321).  [PMID:] [10.1016/j.apcatb.2022.122321]
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41. Cheng He, Jiaxin Ma, Huan Xu, Changzi Ge, Ziru Lian.  (2022)  Selective capture and determination of doxycycline in marine sediments by using magnetic imprinting dispersive solid-phase extraction coupled with high performance liquid chromatography.  MARINE POLLUTION BULLETIN,  184  (114215).  [PMID:36307947] [10.1016/j.marpolbul.2022.114215]
42. Ling Hu, Zhiwen Wang, Yingzhang Shi, Cheng Liu, Yidong Hou, Jinhong Bi, Ling Wu.  (2022)  Coordination activation enhanced photocatalytic performance for levofloxacin degradation over defect-rich WO3 nanosheets.  Journal of Environmental Chemical Engineering,  10  (108738).  [PMID:] [10.1016/j.jece.2022.108738]
43. Xufei Li, Ting Chen, Yanling Qiu, Zhiliang Zhu, Hua Zhang, Daqiang Yin.  (2023)  Magnetic dual Z-scheme g-C3N4/BiVO4/CuFe2O4 heterojunction as an efficient visible-light-driven peroxymonosulfate activator for levofloxacin degradation.  CHEMICAL ENGINEERING JOURNAL,  452  (139659).  [PMID:] [10.1016/j.cej.2022.139659]
44. Zhenyu Lu, Gongke Li, Yufei Hu.  (2022)  A Tb3+ functionalized triazine-porous organic framework as a ratiometric fluorescent sensor for determination of ciprofloxacin in aquatic products.  NEW JOURNAL OF CHEMISTRY,  46  (40): (19153-19160).  [PMID:] [10.1039/D2NJ03657F]
45. Jingwei Yan, Lin Gong, Senyou Chai, Cong Guo, Wei Zhang, Hongyou Wan.  (2022)  Insights into a newly discovered mechanism for 1O2 formation in a chlorine ion-mediated sulfate radical-advanced oxidation process system for levofloxacin degradation in an aqueous solution.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122016).  [PMID:] [10.1016/j.seppur.2022.122016]
46. Ming Liu, Ran Cen, Ji-Hong Lu, Tie-Hong Meng, Chun-Rong Li, Carl Redshaw, Timothy J. Prior, Zhu Tao, Xin Xiao.  (2022)  Cucurbit[6]uril-based carbon dots for recognizing L-tryptophan and capecitabine.  Materials Chemistry Frontiers,  6  (19): (2859-2868).  [PMID:] [10.1039/D2QM00589A]
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50. Lizhen Qiao, Yuan Tao, Wang Yao, Jieyu Zhao, Yang Yan.  (2022)  A magnetic ionic liquid based vortex-assisted dispersive liquid-liquid microextraction coupled with back-extraction for the enrichment of fluoroquinolone antibiotics.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  219  (114903).  [PMID:35759827] [10.1016/j.jpba.2022.114903]
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