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levoketoconazole , Cytochrome P450 11A1 inhibitor, CAS No.142128-57-2, Cytochrome P450 11A1 inhibitor

  • Moligand™
Item Number
L611508
Grouped product items
SKUSizeAvailabilityPrice Qty
L611508-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
L611508-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,001.90

Basic Description

Synonymsketoconazole|Nizoral|Levoketoconazole|Panfungol|Ketoderm|Fungarest|Fungoral|Ketoisdin|Extina|Orifungal M|Ketoconazol|Ketozole|Normocort|65277-42-1|(-)-Ketoconazole|142128-57-2|Ketoconazolum|2S,4R Ketoconazole|2S,4R-Ketoconazole|COR-003|Xolegel|(2S,4R)-ket
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionCytochrome P450 11A1 inhibitor

Product Properties

ALogP4.3

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP11B1 Tclin Cytochrome P450 11B1, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP17A1 Tclin Steroid 17-alpha-hydroxylase/17,20 lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
INCHI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
InChi Key XMAYWYJOQHXEEK-ZEQKJWHPSA-N
Canonical SMILES CC(=O)N1CCN(CC1)c1ccc(cc1)OC[C@@H]1CO[C@@](O1)(Cn1ccnc1)c1c(cc(cc1)Cl)Cl
Isomeric SMILES CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@@H]3CO[C@@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID 47576
Molecular Weight 531.4

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators