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LM22B 10 - ≥98%(HPLC), high purity , CAS No.342777-54-2
TrkB and TrkC agonist; brain penetrant
Basic Description Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms LM22B-10 is a brain penetrant, potent and selective TrkB and TrkC neurotrophin receptors agonist that improves cell survival and potently accelerated neurite outgrowth. LM22B-10 inhibits binding of BDNF to TrkB-expressing cells and NT-3 to TrkC-expressing Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Names and Identifiers IUPAC Name 2-[4-[[4-[bis(2-hydroxyethyl)amino]phenyl]-(4-chlorophenyl)methyl]-N-(2-hydroxyethyl)anilino]ethanol INCHI InChI=1S/C27H33ClN2O4/c28-24-7-1-21(2-8-24)27(22-3-9-25(10-4-22)29(13-17-31)14-18-32)23-5-11-26(12-6-23)30(15-19-33)16-20-34/h1-12,27,31-34H,13-20H2 InChi Key QCXQLSGBOUUVNH-UHFFFAOYSA-N Canonical SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO Isomeric SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO PubChem CID 542158 Molecular Weight 485.02
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 48.5, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 4.85, Max Conc. mM: 10
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F2303098