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Lodoxamide - ≥98%, high purity , CAS No.53882-12-5, Agonist of GPR35

  • Moligand™
  • ≥98%
Item Number
L353943
Grouped product items
SKUSizeAvailabilityPrice Qty
L353943-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$37.90
L353943-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$52.90
L353943-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$81.90
L353943-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$137.90
L353943-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$187.90
View related series
GPR35 Agonist

Basic Description

SynonymsLodoxamide|53882-12-5|Lodoxamidum|Lodoxamida|2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid|Lodoxamidum [INN-Latin]|Lodoxamida [INN-Spanish]|UNII-SPU695OD73|SPU695OD73|DTXSID9057767|N,N'-(2-Chlor-5-cyan-3-phenylen)dioxamsaeure|U-42585E (free
Specifications & PurityMoligand™, ≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of GPR35

Associated Targets

GPR35 Tchem G-protein coupled receptor 35 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid
INCHI InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)
InChi Key RVGLGHVJXCETIO-UHFFFAOYSA-N
Canonical SMILES C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N
Isomeric SMILES C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N
PubChem CID 44564
Molecular Weight 311.63

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityHygroscopic
Melt Point(°C)>219° C (dec.)

Related Documents

References

1. Park SJ, Lee SJ, Nam SY, Im DS.  (2018)  GPR35 mediates lodoxamide-induced migration inhibitory response but not CXCL17-induced migration stimulatory response in THP-1 cells; is GPR35 a receptor for CXCL17?.  Br J Pharmacol,  175  (1): (154-161).  [PMID:29068046]

Solution Calculators