Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
L353943-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $37.90 | |
L353943-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $52.90 | |
L353943-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $81.90 | |
L353943-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $137.90 | |
L353943-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $187.90 |
Synonyms | Lodoxamide|53882-12-5|Lodoxamidum|Lodoxamida|2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid|Lodoxamidum [INN-Latin]|Lodoxamida [INN-Spanish]|UNII-SPU695OD73|SPU695OD73|DTXSID9057767|N,N'-(2-Chlor-5-cyan-3-phenylen)dioxamsaeure|U-42585E (free |
---|---|
Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of GPR35 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | 2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid |
---|---|
INCHI | InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21) |
InChi Key | RVGLGHVJXCETIO-UHFFFAOYSA-N |
Canonical SMILES | C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N |
Isomeric SMILES | C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N |
PubChem CID | 44564 |
Molecular Weight | 311.63 |
CAS Registry No. | 53882-12-5 |
---|---|
ChEMBL Ligand | CHEMBL1201266 |
PubChem CID | 44564 |
DrugCentral Ligand | 3325 |
GPCRdb Ligand | lodoxamide |
RCSB PDB Ligand | WYB |
Enter Lot Number to search for COA:
Sensitivity | Hygroscopic |
---|---|
Melt Point(°C) | >219° C (dec.) |
1. Park SJ, Lee SJ, Nam SY, Im DS. (2018) GPR35 mediates lodoxamide-induced migration inhibitory response but not CXCL17-induced migration stimulatory response in THP-1 cells; is GPR35 a receptor for CXCL17?. Br J Pharmacol, 175 (1): (154-161). [PMID:29068046] |