Lonapalene (RS4317) is a topically effective 5-lipoxygenase ( 5-LO ) inhibitor.
In Vitro
Lonapalene (RS4317) may be useful in the treatment of psoriasis, and that leukotriene B4 is a relevant mediator of the pathology of this disease. MCE has not independently confirmed the accuracy of these methods. They are for reference only.