Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab182786-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab182786-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $319.90 | |
| Ab182786-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $779.90 | |
| Ab182786-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,239.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Loncastuximab (anti-CD19) - Primary antibody, specific to CD19, Human IgG1 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | CD19 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Loncastuximab (anti-CD19) is an anti-CD19 monoclonal antibody. Loncastuximab (anti-CD19) shows antitumor activity and has potential application in non-Hodgkin's lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 192.5 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 1875032-68-0 |
Loncastuximab (anti-CD19) (Ab182786) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 with Loncastuximab (anti-CD19) (Ab182786) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Loncastuximab (anti-CD19) (Ab182786) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 (red) with Loncastuximab (anti-CD19) (Ab182786) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Loncastuximab (anti-CD19) (Ab182786) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD19 (red) with Loncastuximab (anti-CD19) (Ab182786). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Loncastuximab (anti-CD19) (Ab182786) - SEC
The purity of Loncastuximab (anti-CD19) (Ab182786) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0607463 | Certificate of Analysis | Jun 28, 2024 | Ab182786 |
| ZJ24F0607462 | Certificate of Analysis | Jun 28, 2024 | Ab182786 |
| ZJ24F0607461 | Certificate of Analysis | Jun 28, 2024 | Ab182786 |
