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Low endotoxin gelatin from porcine skin - gel strength 260-330 (Bloom),

  • gel strength 260-330 (Bloom), <10 EU/g Endotoxin
Item Number
L434330
Grouped product items
SKUSizeAvailabilityPrice Qty
L434330-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$374.90
L434330-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,862.90

Basic Description

SynonymsEpinephrine hydrochloride|55-31-2|Epinephrine HCl|l-Epinephrine hydrochloride|Adrenaline hydrochloride|Adrenalin chloride|Adrenaline chloride|l-Epinephrine.HCl|Epinephrine chloride|l-Adrenaline chloride|l-Epinephrine chloride|Adrenalin hydrochloride|Epine
Specifications & Puritygel strength 260-330 (Bloom), <10 EU/g Endotoxin
Legal InformationbeMatrix is a trademark of Nitta Gelatin
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Application

Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Low endotoxin gelatin from porcine skin, gel strength 300 bloom is a high bloom (high molecular weight) gelatin featuring less than 10 endotoxin units (EU) per gram. Endotoxins primarily consist of lipopolysaccharides from the outer membrane of gram-negative bacteria. Once in the bloodstream, endotoxins are capable of eliciting a strong immune response, potentially leading to fever, shock, a drop in blood pressure, and even potentially death. In addition to this immune response, several reports suggest endotoxins may also damage various types of cells. To avoid adverse effects, raw materials should contain the lowest level of endotoxins possible when used in biomedical or regenerative medicine research applications. This low endotoxin gelatin is derived from alkaline-treated porcine skin and has a variety of potential applications in the fields of regenerative medicine, medical devices, and tissue engineering research.

Names and Identifiers

IUPAC Name 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride
INCHI InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H/t9-;/m0./s1
InChi Key ATADHKWKHYVBTJ-FVGYRXGTSA-N
Canonical SMILES CNCC(C1=CC(=C(C=C1)O)O)O.Cl
Isomeric SMILES CNC[C@@H](C1=CC(=C(C=C1)O)O)O.Cl
WGK Germany 3
RTECS LX8580000
PubChem CID 441411

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

WGK Germany 3
RTECS LX8580000

Related Documents

References

1. J G Brock-Utne,S L Gaffin.  (1989-02-01)  Endotoxins and anti-endotoxins (their relevance to the anaesthetist and the intensive care specialist)..  Anaesthesia and intensive care,  17  ((1)): (49-55).  [PMID:2653093]
2. E J Ziegler,J A McCutchan,J Fierer,M P Glauser,J C Sadoff,H Douglas,A I Braude.  (1982-11-11)  Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli..  The New England journal of medicine,  307  ((20)): (1225-1230).  [PMID:6752708]
3. J M Harlan,L A Harker,M A Reidy,C M Gajdusek,S M Schwartz,G E Striker.  (1983-03-01)  Lipopolysaccharide-mediated bovine endothelial cell injury in vitro..  Laboratory investigation; a journal of technical methods and pathology,  48  ((3)): (269-274).  [PMID:6827807]
4. T Kirikae,H Tamura,M Hashizume,F Kirikae,Y Uemura,S Tanaka,T Yokochi,M Nakano.  (1997-05-01)  Endotoxin contamination in fetal bovine serum and its influence on tumor necrosis factor production by macrophage-like cells J774.1 cultured in the presence of the serum..  International journal of immunopharmacology,  19  ((5)): (255-262).  [PMID:9439764]
5. Shoko Yamamoto,Yuta Matsushima,Yoshitaka Kanayama,Azusa Seki,Haruya Honda,Hidero Unuma,Yasuo Sakai.  (2017-02-09)  Effect of the up-front heat treatment of gelatin particles dispersed in calcium phosphate cements on the in vivo material resorption and concomitant bone formation..  Journal of materials science. Materials in medicine,  28  ((3)): (48-48).  [PMID:28176192]
6. K W Brunson,G L Nicolson.  (1978-01-01)  Lipopolysaccharide effects on sensitive and resistant variant Chinese hamster ovary cell lines..  Journal of supramolecular structure,  ((2)): (231-242).  [PMID:748676]
7. J Ongrádi,G Kulcsár,L Bertók.  (1984-01-01)  Toxicity of microbial products in cell culture..  Folia microbiologica,  29  ((6)): (450-454).  [PMID:6441761]

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