Antioxidant, anti-inflammatory and anticancer flavonoid. Free radical scavenger and apoptosis inducer. Inhibits TNF-α induced COX-2 expression and supresses PI3K/Akt, NF-κB cell survival pathways.
Storage Temp
Store at 2-8°C,Argon charged
Shipped In
Wet ice
Grade
analytical standard, Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of TAS2R14;Agonist of TAS2R39
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Associated Targets
CNBD2Tdark Cyclic nucleotide-binding domain-containing protein 2 0 Activities
1.Lehane AM, Saliba KJ. (2008) Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite.. BMC Res Notes, 1 (3):(26). [PMID:18710482]
2.Fei J et al.. (2019) Luteolin inhibits IL-1ß-induced in?ammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model.. Biomed Pharmacother, 109 (1586-1592). [PMID:30551412]
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D2430090
