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LY2389575 , CAS No.L611638, Allosteric modulator of mGlu 3 receptor

  • Moligand™
Item Number
L611638
Grouped product items
SKUSizeAvailabilityPrice Qty
L611638-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
L611638-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,001.90

Basic Description

SynonymsLY 2389575;LY-2389575
Specifications & PurityMoligand™
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of mGlu 3 receptor

Associated Targets

GRM2 Tchem Metabotropic glutamate receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM3 Tchem Metabotropic glutamate receptor 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (3S)-1-(5-bromopyrimidin-2-yl)-N-[(2,4-dichlorophenyl)methyl]pyrrolidin-3-amine
INCHI InChI=1S/C15H15BrCl2N4/c16-11-7-20-15(21-8-11)22-4-3-13(9-22)19-6-10-1-2-12(17)5-14(10)18/h1-2,5,7-8,13,19H,3-4,6,9H2/t13-/m0/s1
InChi Key PXQNLQLMRMROSB-ZDUSSCGKSA-N
Canonical SMILES Clc1ccc(c(c1)Cl)CN[C@H]1CCN(C1)c1ncc(cn1)Br
Isomeric SMILES C1CN(C[C@H]1NCC2=C(C=C(C=C2)Cl)Cl)C3=NC=C(C=N3)Br
PubChem CID 11503055

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Sheffler DJ, Wenthur CJ, Bruner JA, Carrington SJ, Vinson PN, Gogi KK, Blobaum AL, Morrison RD, Vamos M, Cosford ND et al..  (2012)  Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe (ML289) derived from a closely related mGlu5 PAM..  Bioorg Med Chem Lett,  22  (12): (3921-5).  [PMID:22607673]

Solution Calculators